Nouvelle déclaration d'incident
No de la demande: 2019-0329
Numéro de référence du titulaire d'homologation: USA-BAYERBAH-2018-US0071198 (Report 537856)
Nom du titulaire (nom légal complet, aucune abbréviation): Bayer inc
Adresse: 2920 Matheson Blvd
Ville: Mississaugua
État: ON
Pays: Canada
Code postal /Zip: L4W 5R6
Incident chez un animal domestique
Pays: UNITED STATES
État: NEW YORK
Inconnu
ARLA No d'homologation ARLA No de la demande d'homologation EPA No d'homologation. 11556-155
Nom du produit: Seresto collar unknown
Autre (préciser)
COLLAROui
Autres unités: COLLAR
Site: Animal / Usage sur un animal domestique
Inconnu
Propriétaire de l'animal
Dog / Chien
Labrador Retriever
1
Femme
Inconnu
Inconnu
Cutanée
Unknown / Inconnu
Unknown / Inconnu
Système
Persisted until death
Non
Non
Mort
Treatment / Traitement
(p.ex. description des symptômes tels que la fréquence et la gravité
On an unknown date post application, in approximately 2017, the collar was chewed off of the dog by a housemate. On an unknown date post removal, in approximately 2017, the owner removed an unspecified number of ticks from the dog. On an unknown date post tick removal, in approximately Dec-2017, the dog was diagnosed with borreliosis. On approximately 25-Dec-2017, the dog died due to unknown circumstances. No known necropsy was performed. Due to the sensitive nature of the communication, specific relevant event details were not obtained, nor will such be sought. The reason for the initial call was to discuss the use of Seresto in the owner's current dog and not to report the death of the patient. No further information is expected. This case is closed.
Mort
N - Unlikely Ticks will be killed and fall off the host within 24 to 48 hours after infestation without having had a blood meal, as a rule. However, attachment of single ticks and even sucking of blood and thus transfer of tick borne disease (borreliosis) cannot be excluded while the collar is worn and simply reflects the labeled claim of efficacy that is not 100% against ticks especially when infestation pressure is high. Thus, infection with tick borne diseases despite wearing a collar can occur exceptionally and is consistent with the product's claimed efficacy as addressed in the product information. Moreover, in this case collar was chewed off of the dog by a housemate before ticks were detected and number and status of ticks are unknown. Reported death is not expected following appropriate topical product application as inconsistent with product's pharmacological profile. Oral exposure to the collar is not expected to cause serious signs either. An overdose of 5 collars around the neck was investigated in adult cats and dogs for an 8 months period and in 10 week old kittens and 7 week old puppies for a 6 months period without causing serious signs. This is supported by the extremely low systemic exposure with imidacloprid and flumethrin, particularly during the first week after application and also thereafter. Death maybe related to diagnosed borreliosis. Furthermore the reason for the initial call was to discuss the use of Seresto in the owner's current dog and not to report the death of the patient. Overall, a product involvement is considered unlikely.