Nouvelle déclaration d'incident
No de la demande: 2016-7526
Numéro de référence du titulaire d'homologation: 160145560
Nom du titulaire (nom légal complet, aucune abbréviation): Wellmark International
Adresse: 100 Stone Road West, Suite 111
Ville: Guelph
État: Ontario
Pays: Canada
Code postal /Zip: N1G5L3
Incident chez un animal domestique
Pays: UNITED STATES
État: MISSOURI
ARLA No d'homologation ARLA No de la demande d'homologation EPA No d'homologation. 2724-803-270
Nom du produit: Adams Flea and Tick Spray for Dogs and Cats
Liquide
Oui
Inconnu
Site: Animal / Usage sur un animal domestique
Inconnu
Propriétaire de l'animal
Cat / Chat
Siamese
1
Homme
5.0
12.0
lbs
Cutanée
>2 hrs <=8 hrs / >2 h <=8 h
Unknown / Inconnu
Système
Persisted until death
Non
Non
Mort
Treatment / Traitement
(p.ex. description des symptômes tels que la fréquence et la gravité
On September 28, 2016 the cat developed head shaking. That evening, the owner bathed the cat (liquid dish washing detergent (LDWD)). On September 29, 2016 the owner found the cat dead in the morning. The owner then contacted the Animal Product Safety Service (APSS). The APSS veterinarian stated we would not expect death as a direct result of the product use. The APSS veterinarian recommended a necropsy. The APSS veterinarian discussed with the owner taking the cat's body to the veterinary clinic for necropsy submission and having the veterinary clinic call for information regarding instructions. Later that morning, the attending veterinarian called the APSS to discuss necropsy submission instructions.
Mort
The APSS veterinarian stated that the substance was considered to have a doubtful likelihood of causing the clinical situation. On October 4, 2016 the attending veterinarian called the APSS to state she had received a copy of the necropsy results. The gross necropsy report revealed the following morphologic diagnosis: heart (left ventricle) showed mild concentric hypertropy; lung showed diffuse, moderate edema; liver showed diffuse, moderate congestion; urinary bladder showed multifocal to coalescing, moderate, acute cystitis (presumptive); small intestine (jejunum) showed mild tapeworm parasitism; pancreas showed multifocal to coalescing, mild, acute pancreatitis; and right eye showed mild hyphema. Gross lesions observed in this animal were unspecific and a cause of death could not be determined. The histopath necropsy report revealed a morphologic diagnosis: the heart (left ventricle and interventricular septum) showed multifocal, moderate, myocardial disarray and fibrosis; the lung showed multifocal to coalescing, moderate, histiocytic interstitial pneumonia with type II pneumocyte hyperplasia and smooth muscle hypertrophy and hyperplasia. The histopathologic findings are highly suggestive of a chronic cardiac disease consistent with feline hypertrophic cardiomyopathy. Furthermore, pulmonary lesions were also characterized by a chronic process of unknown cause. It is uncertain, however, if the observed alterations elicited clinical abnormalities that contributed to the cause of death of this animal. Gross lesions observed in the urinary bladder and pancreas represented alterations of minimal significance on microscopic examination. Shortly after reviewing the report, the APSS veterinarian called the attending veterinarian back to discuss the necropsy and stated it was okay to give the owner a copy of the report. The APSS veterinarian also stated she would call the owner to discuss the necropsy results. The APSS veterinarian called the owner to go over the results and stated that it was highly suggestive of a chronic cardiac disease consistent with feline hypertrophic cardiomyopathy. The APSS veterinarian also stated the report revealed pulmonary lesions characterized by a chronic process of unknown cause. The APSS veterinarian discussed that underlying disease contributed to the death of the cat, spraying of the product may have been a trigger. The owner requested a copy of the necropsy report. The APSS veterinarian stated she was unable to mail a copy, but a copy could be obtained from the attending veterinary clinic. The APSS veterinarian called the attending veterinary clinic to let them know that the owner was interested in obtaining a copy of the necropsy results. The APSS veterinarian stated that hypertropic cardiomyopathy was considered to have a high likelihood of causing the clinical situation.