Nouvelle déclaration d'incident
No de la demande: 2015-3924
Numéro de référence du titulaire d'homologation: 2015TH264
Nom du titulaire (nom légal complet, aucune abbréviation): Bayer Inc
Adresse: 2920 Matheson Blvd
Ville: Mississauga
État: ON
Pays: Canada
Code postal /Zip: L9W 5R6
Incident chez un animal domestique
Pays: UNITED STATES
État: UNKNOWN
ARLA No d'homologation ARLA No de la demande d'homologation EPA No d'homologation. 11556-155
Nom du produit: Seresto Collar - cat
Autre (préciser)
CollarOui
Autres unités: collar
Site: Animal / Usage sur un animal domestique
Autre
Cat / Chat
Domestic short hair
1
Homme
5
13.6
lbs
Cutanée
>15 min <=2 hrs / >15 min <=2 h
>30 min <=2 hrs / >30 min <=2 h
Système
Persisted until death
Oui
Oui
1
Day(s) / Jour(s)
Mort
Treatment / Traitement
(p.ex. description des symptômes tels que la fréquence et la gravité
On 26Jul2013, an approximately 5 year old, 13.6 pound, neutered, male, Domestic Shorthair, in fair condition, with a history of a severe flea infestation and severely decayed teeth, had one Seresto Cat Collar (Flumethrin-Imidacloprid) placed around his neck by the owner. Approximately one hour after the collar was placed, the cat started drooling and behaving uncharacteristically. Approximately two hours later, the owner removed the collar from the cat. On 29Jul2013, the cat was examined at the veterinary clinic and a malocclusion was diagnosed. The owner declined pre-anesthetic bloodwork. The cat was sedated with tiletamine/zolazepam and maintained on inhalant isoflurane gas. Two severely decayed teeth were extracted. The cat was then administered an injection of penicillin and an unspecified anti-inflammatory. The cat was then placed in a kennel to wake up from the procedure; recovery was uneventful. However, 1.5 hours later, the cat was found dead in the cage. On 30 Jul 2013, a necropsy was performed and the cause of death was perianesthetic death. No further information expected. This case is closed
Mort
N- Unlikely. Reported behavioural sign may be a reaction to uncomfortable feeling of collar, particularly in individuals not used to it. Drooling also not expected following correct product application, and as no oral product exposure was reported. Time to onset short and for behavioural disorder and drooling compatible with product application. However, reported musculoskeletal disorder and death not expected after use of the product as inconsistent with pharmaco- oxicological product profile. Cat has history of decayed teeth, which probably is cause of jaw disorder or vice versa, and may also be cause of drooling. Cat had anaesthesia and surgery prior to death, which are probable cause. Time to onset for latter signs also argues against product relation as collar had been already removed approx. 3 days before. Necropsy diagnosis of perianesthetic death may lead to the conclusion that the felines illnesses combined with anesthesia contributed to the feline's death. Overall, a product relation thus is deemed to be unlikely