Nouvelle déclaration d'incident
No de la demande: 2013-6499
Numéro de référence du titulaire d'homologation: 130112403
Nom du titulaire (nom légal complet, aucune abbréviation): Wellmark International
Adresse: 100 Stone Road West, Suite 111
Ville: Guelph
État: Ontario
Pays: Canada
Code postal /Zip: N1G5L3
Incident chez un animal domestique
Pays: UNITED STATES
État: OREGON
Inconnu
ARLA No d'homologation ARLA No de la demande d'homologation EPA No d'homologation. 2724-814
Nom du produit: Kirkland Signature Flea And Tick Control For Cats 5lbs and over
Liquide
Oui
Unités: mL
Site: Animal / Usage sur un animal domestique
Propriétaire de l'animal
Cat / Chat
Domestic Shorthair
1
Femme
11.0
9.0
lbs
Cutanée
>3 days <=1 wk / >3 jours <=1 sem
Unknown / Inconnu
Système
Persisted until death
Inconnu
Inconnu
Mort
Treatment / Traitement
(p.ex. description des symptômes tels que la fréquence et la gravité
Sometime after the exposure to the product on August 8, 2012 or on August 9, 2013 the owner noticed that the cat was symptomatic. On August 11, 2013 the owner bathed the cat. On the morning of August 12, 2013 the owner took the cat to the veterinarian. Later that day the owner contacted the Animal Product Safety Service (APSS) to obtain help. The APSS veterinarian stated that contact hypersensitivity could occur, as with any topical exposure. The APSS veterinarian also stated that if the product was ingested, gastrointestinal (GI) upset and/or a taste reaction could occur. The APSS assistant recommended that the owner have his veterinarian call for information.
Mort
On November 5, 2013 diagnostic laboratory staff contacted the APSS to update the case and provide a necropsy report. Per the diagnostic laboratory, the cat died suddenly on August 13, 2013 and was brought into the veterinary clinic that day; the cat's body was then shipped to the diagnostic laboratory for a necropsy. The necropsy results revealed that autolysis was prominent in the cat and precluded any meaningful interpretation of the many tissue changes; the gross necropsy and histopathology studies confirmed that at least mild hepatic lipidosis was present in the cat, and this might be significant if there were any clinical signs suggestive of feline hepatic lipidosis. As for the possible pyrethroid toxicity from the application of the flea product, it could be a possibility; cats, unlike other vertebrates, cannot metabolize and detoxify pyrethroid derivatives due to the absence of a Beta-Glucuronidase enzyme in the liver, and toxicity can occur. However, pyrethroid toxicity does not produce any gross or histologic changes. No other underlying disease problems were found in the cat aside from the incidental finding of a black colored trichobezoar of 5 centimeters (cm) x 3 cm x 3 cm dimension in the stomach.