Nouvelle déclaration d'incident
No de la demande: 2013-3237
Numéro de référence du titulaire d'homologation: 2013AM142
Nom du titulaire (nom légal complet, aucune abbréviation): Bayer Inc
Adresse: 77 Belfield Rd
Ville: Toronto
État: ON
Pays: Canada
Code postal /Zip: M9W 1G6
Incident chez un animal domestique
Pays: UNITED STATES
État: UNKNOWN
ARLA No d'homologation ARLA No de la demande d'homologation EPA No d'homologation. 11556 152
Nom du produit: Advantage II large cat
Liquide
Oui
Unités: mL
Site: Animal / Usage sur un animal domestique
Propriétaire de l'animal
Cat / Chat
Domestic shorthair
1
Homme
9
14
lbs
Cutanée
Unknown / Inconnu
>24 hrs <=3 days / >24 h <=3 jours
Système
Unknown / Inconnu
Oui
Non
Mort
Treatment / Traitement
(p.ex. description des symptômes tels que la fréquence et la gravité
11July2011 owner applied Advantage II Large Cat to Gabrielle a 9 year old male Domestic Shorthair that weighs 14 pounds for flea infestation. Less then 8 hours after application this feline lethargic. On 14July2011 this feline was not willing to walk. Veterinary examination this cat presented at the clinic with white / pale mucous membranes, body temperature of 94.8 degrees, obese according to the doctor. This feline weighed 14.8 pounds and should have weighed about 11 pounds. That was the first time this doctor had seen this feline. This feline died during the examination process. The DVM drew blood (which was very thin) and sent it out - a CBC and path report are pending. The doctor wants to rule out a flea-borne disease. No necropsy was preformed. Update 20.07.2011: On 16July2011 the veterinarian got CBC results from Antech: Low RBC 3.96 (5.92-9.93), Low Hemaglobin 6.8 (9.3-15.9), Low Hematocrit 21.9 (29-48), Low Platelet count 15 (200-500), Low Neutrophils 2064 (2500-8500), Antech recommended PCR test and that is pending. Blood smear=Poylchromasia is almost moderate but still not enough to raise the pcb. Cytauxzoon organisms were not identified. PCR was negative. Update 09.09.2011: The veterinarian received results for Past Panel PCR Feline Haemotropic Mycoplasma Panal: Mycoplasma hemofelis negative, Mycoplasma Haemominutum Negative, and Mycoplasma Turicensis Negative. No more information expected.
Mort
Lethargy may exceptionally occur in particular sensitive animals. Other signs not expected after topical product application as inconsistent with pharmaco-toxicological product profile. Onset time of 3 days for other signs, argues against anaphylactic reaction. Lab results indicate also other cause, see low values for almost all parameters. Samples negative for mycoplasma. However, product relation furtheron considered unlikely.