Nouvelle déclaration d'incident
No de la demande: 2011-5329
Numéro de référence du titulaire d'homologation: 32012178
Nom du titulaire (nom légal complet, aucune abbréviation): Monsanto Canada Inc.
Adresse: 180 Kent Street, Suite 810
Ville: Ottawa
État: ON
Pays: Canada
Code postal /Zip: K1P 0B6
Incident chez l'humain
Pays: UNITED STATES
État: ARIZONA
ARLA No d'homologation ARLA No de la demande d'homologation EPA No d'homologation. 524-445
Nom du produit: Roundup Herbicide
Liquide
Non
Inconnu
Autre
Sexe: Homme
Âge: Unknown / Inconnu
Système
Unknown / Inconnu
Oui
Oui
Inconnu
Non professionnel
Empoisonnement par ingestion d'un produit
Orale
Unknown / Inconnu
Unknown / Inconnu
Call received 5 days post exposure, from a resident MD from another Poison Center concerning a man that stated he drank diluted weed killer that was from a concentrate and vodka last Saturday. The man arrived to the ER by ambulance after being found down in a shed in his backyard. No container was available. EMS saw a spray cannister that the man had filled with product for home use. Both the man and his wife say it was a diluted weed killer from concentrate but no name or ingredients given. Reports of drinking 150-350 ml. The MD contacted MRPC with report of the man having hypotension requiring use of vasopressors, metabolic acidosis, increased lactate, renal impairment requiring continuous renal replacement therapy (CRRT) for 2 days. The man was intubated, sedated and placed on a ventilator for 5-6 days before being extubated. Supportive care with IV fluids, vasopressors, CRRT, sodium bicarbonate done. The man also had lab evidence of an anion gap, osmolar gap and was treated with fomepizole. One time dose of intralipids given. By day 4, the man was showing gradual signs of improvement as evidenced by decreased need for vasopressors, CRRT, and improved neuro status. No evidence of GI injury. MRPC was contacted on day 6 for information concerning Roundup product. MRPC discussed the product toxicity. Difficult to determine the certainty of the exact cause for the man's course of effects. If it is assumed that he ingested a large amount of a concentrated Roundup product, the symptoms of hypotension requiring vasopressors resulting in increased lactate leading to metabolic acidosis with evidence of renal impairment is consistent with ingestion of concentrated surfactant. If it was a product that contained diquat dibromide , renal impairment is the end point of toxicity. No further follow up obtained.
Majeure
This incident appears to be an attempted suicide but it is not clear from the information provided, therefore it is being reported.