New incident report
Incident Report Number: 2024-2827
Registrant Reference Number: CAN-ZZELANCO-CA2024_001037
Registrant Name (Full Legal Name no abbreviations): Elanco
Address: 1919 Minnesota Court, Suite 401
City: Mississauga
Prov / State: ON
Country: Canada
Postal Code: L5N 0C9
Domestic Animal
Country: CANADA
Prov / State: BRITISH COLUMBIA
PMRA Registration No. PMRA Submission No. EPA Registration No. Unknown
Product Name: Advantage II pipette size unknown
Yes
Unknown
Site: Animal / Usage sur un animal domestique
Unknown
Medical Professional
Dog / Chien
Australian Shepherd / Poodle
1
Male
3
28.4
kg
Skin
>1 wk <=1 mo / > 1 sem < = 1 mois
>1 wk <=1 mo / > 1 sem < = 1 mois
System
Unknown / Inconnu
Yes
No
Not recovered / Non rétabli
Treatment / Traitement
(eg. description of the frequency and severity of the symptoms
On 19Jan2024, the 3 year old, 28.4 kg, neutered male, Australian Shepherd/Poodle crossbred dog, with concomitant fleas and a history of seizures every 6 months since 2022, presented, at the veterinary clinic, for acute onset of hematuria. Urinalysis was performed, urine was red and cloudy, trace protein, white and red blood cells (collectively coded under Haematuria). The owner reported the dog was also pruritic. It is unknown if the pruritus was at the application site. The dog was sedated with Dexmedetomidine and abdominal radiographs were taken. No concerning findings were identified in the radiographs. An in clinic urinalysis was performed and results showed hematuria. The dog was given an intramuscular injection of atipamezole hydrochloride to reverse the sedation. Chinese herbs (details not provided) were dispensed as treatment. On 21Jan2024 the hematuria resolved. Gabapentin was dispensed in preparation for the following days cystocentesis. On 22Jan2024 the dog was given Dexmedetomidine and Butorphanol by intravenous route. The dog had an abdominal ultrasound, with no identified abnormal findings. Urine was collected via cystocentesis and sent for a urine culture. On 01Feb2024 the results of the urine culture were negative. On 24Feb2024 the dog had hematuria and was pruritic. It is unknown if the pruritus was at the application site. The pet owner administered Chinese herbs to the dog. On 25Feb2024 the dog recovered. On 04Apr2024 the dog developed hematuria and pruritus on the abdomen. On an unknown date the hematuria resolved. On 08Apr2024 the dog vomited bile one time and then recovered. On 15Apr2024 the dog was seen by the veterinarian. The pruritus had improved but not resolved and the dog had dry scales in the fur on the dorsal lumbar back (coded as dry skin). At the tme of completing this report the hematuria and vomiting had resolved. The pruritus and dry skin were ongoing.
Moderate