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Consumer Product Safety

Incident Report

Subform I: General Information

1. Report Type.

New incident report

Incident Report Number: 2022-3645

2. Registrant Information.

Registrant Reference Number: MULTIPLESTUDIES01-2022-07-22

Registrant Name (Full Legal Name no abbreviations): Bayer CropScience Inc.

Address: Suite 200, 160 Quarry Park Boulevard SE


Prov / State: AB

Country: Canada

Postal Code: T2C 3G3

3. Select the appropriate subform(s) for the incident.

Scientific Study

4. Date registrant was first informed of the incident.

5. Location of incident.

6. Date incident was first observed.

Product Description

7. a) Provide the active ingredient and, if available, the registration number and product name (include all tank mixes). If the product is not registered provide a submission number.


PMRA Registration No. 20537      PMRA Submission No.       EPA Registration No.


  • Active Ingredient(s)

7. b) Type of formulation.

Application Information

8. Product was applied?


9. Application Rate.

10. Site pesticide was applied to (select all that apply).

11. Provide any additional information regarding application (how it was applied, amount applied, the size of the area treated etc).

To be determined by Registrant

12. In your opinion, was the product used according to the label instructions?


Subform VII: Scientific Study

1. Study Reference

Title Effects of metribuzin tech. (Acute contact and oral) on honey bees (Apis mellifera L.) in the laboratory

Date 11-NOV-14

2. a) Is an extension needed to translate the document?


3. Type of incident identified in the study

New health or environmental hazard

4. Describe the incident identified in the study (e.g. study demonstrates an increased risk to non-Hodgkin's Lymphoma after exposure to pesticide X)

The studies are all being submitted as information for new study types or species. M-501967-01-1, M-540903-02-2 and M-619414-01-2: studies submitted to fulfill the data requirements for adult honey bees acute oral and contact toxicity, adult honey bee chronic toxicity and larval honey bee chronic toxicity. M-541125-01-2, M-540205-01-1 and M-540557-01-1 : studies submitted to fulfill the conditional requirement for higher tier (Tier 2/3) testing with honey bees. M-304283-01-1 and M-464882-01-2 : studies submitted as data on a new species. M-497193-01-2 and M-492522-01-1: conditionally required in Canada. Higher tier data for this species are available if requested. M-301381-01-1 and M-459271-01-2: acute and chronic earthworm studies with EP. The chronic study provides a new endpoint for the species/test duration.

5. a) Was the study discontinued before completion?


5. b) Provide the reason for discontinuation

6. If the study is ongoing, what is the expected completion date?

For Registrant use only

7. Provide supplemental information here

This group of studies (with the exception of two of the honey bee studies) were performed to support registration of the formulation Metribuzin SC 600 g/L. This exact formulation is not sold in the US or Canada. In Canada, Bayer sells a formulation under the Sencor brand that is a soluble concentrate (SC) with 480 g/L of metribuzin - this formulation is considered to be similar to the SC 600 formulation.