New incident report
Incident Report Number: 2022-1010
Registrant Reference Number: ProPharma Group case #: 2022SCPU00038313
Registrant Name (Full Legal Name no abbreviations): Syngenta Canada Inc.
Address: 140 Research Lane, Research Park
City: Guelph
Prov / State: Ontario
Country: Canada
Postal Code: N1G4Z3
Human
Country: UNITED STATES
Prov / State: UNKNOWN
Unknown
PMRA Registration No. PMRA Submission No. EPA Registration No. Unknown
Product Name: PARAQUAT TECHNICAL
Liquid
Unknown
Unknown
Other
Sex: Male
Age: >19 <=64 yrs / >19 <=64 ans
System
Persisted until death
Yes
Yes
1
Day(s) / Jour(s)
Non-occupational
Poisoning from ingestion of the pesticide
Unknown
Oral
Unknown / Inconnu
<=30 min / <=30 min
2022SCPU000383013 - Acute paraquat ingestion: undoubtedly responsible Scenario/Substances: A 60 y/o male ingested 16 oz. of undiluted paraquat in an attempt to harm himself after an argument. He experienced immediate nausea and vomiting without hematemesis, followed by shortness of breath and diffuse body pains. He was transported by air ambulance to the ED. Enroute, he was placed on 2L O2 by nasal cannula and given activated charcoal. Past Medical History: High blood pressure, dyslipidemia. Tobacco and alcohol use. Home medications unknown other than acetaminophen with codeine. Physical Exam: Sickly in appearance with tachycardia, tachypnea, and diaphoresis. Breathing was labored, but lungs sounds were clear bilaterally. Dry mucous membranes with abdominal tenderness in bilateral upper quadrants. Alert and oriented with a GCS of 15. BP 144/80, HR 96,RR 32, O2 sat 81% on RA, T 35.4C.Laboratory/Diagnostic Findings: Na 143/K 5.4/Cl 105/CO2 14/BUN 9/Cr1.14/Glu 119/AG 24, AST 37, ALT 77, bilirubin 0.41, INR 1.14, pro-BNP1,342, WBC 16.8/Hgb 15.9/Hct 49.3/PLT 242, ABG-pH 7.25/pCO2 36/pO257/HCO3 15.8/BE -10.5. Serum APAP, ethanol and salicylate not detected. ECG: Sinus rhythm with nonspecific ST-T abnormalities, nonspecific IVCD with LAD; HR 93, QRS 138, QTc 528. Clinical Course: In the ED, his supplemental O2 was removed, and he was started on prednisone and antioxidant therapies with IV NAC and vitamin C. He was admitted to the ICU. Based on the prognosis, the family opted for institution of comfort measures. About 7 h after ingestion,the patient became unresponsive, asystolic and died. Autopsy Findings: Not performed.
Death
The information for this report was received via an external publication and the summary provided here in Section 13 is directly as written by Gummin et al., 2021. Citation: David D. Gummin, James B. Mowry, Michael C. Beuhler, Daniel A. Spyker, Alvin C. Bronstein, Laura J. Rivers, Nathaniel P. T. Pham Julie Weber (2021) 2020 Annual Report of the American Association of Poison Control Centers National Poison Data System (NPDS): 38th Annual Report, Clinical Toxicology, 59:12, 1282-1501. The exact name of the product was not stated in the publication.