New incident report
Incident Report Number: 2021-3606
Registrant Reference Number: USA-BAYERBAH-2021-US0025930 (Report 707853)
Registrant Name (Full Legal Name no abbreviations): Bayer inc
Address: 2920 Matheson Blvd
City: Mississaugua
Prov / State: ON
Country: Canada
Postal Code: L4W 5R6
Domestic Animal
Country: UNITED STATES
Prov / State: TENNESSEE
Unknown
PMRA Registration No. PMRA Submission No. EPA Registration No. 11556-155
Product Name: Seresto Collar Large
Other (specify)
COLLARYes
Other Units: COLLAR
Site: Animal / Usage sur un animal domestique
Animal's Owner
Dog / Chien
Retriever - Labrador crossbred
1
Male
5
11.34
kg
Skin
Oral
Unknown / Inconnu
Unknown / Inconnu
System
Unknown / Inconnu
Unknown
Unknown
Died
Treatment / Traitement
(eg. description of the frequency and severity of the symptoms
On an unspecified date post application, in approximately 2021, the dog exhibited coughing. On 15-Jun-2021, the dog chewed and ingested an unknown amount of the collar. On 16-Jun-2021, the dog developed hematemesis and epistaxis; and died. No necropsy was performed.
Death
O - Unclassifiable/unassessable Reported coughing is not expected and may have numerous causes. Time to onset is unknown. In this case, dog chewed and ingested an unknown amount of the collar. Oral exposure to product may cause mild gastrointestinal signs such as hematemesis. Epistaxis is not expected after oral exposure of the product. Time to onset is short. Death is not expected following appropriate topical product application as inconsistent with products pharmacological profile. Oral exposure to the collar is not expected to cause serious signs either. An overdose of 5 collars around the neck was investigated in adult cats and dogs for an 8 months period and in 10 week old kittens and 7 week old puppies for a 6 months period without causing serious signs. This is supported by the extremely low systemic exposure with imidacloprid and flumethrin, particularly during the first week after application and also thereafter. Additionally, it is unknown if individual was examined by a physician and thus no medical doctors reports or laboratory reports are available. Additionally, it is unknown if animal was examined by veterinarian and thus no diagnostic reports or laboratory reports are available. Time to onset is short for the signs reported after oral exposure of the product. Considering limited information (e.g. health status, medical history and necropsy results are unknown), a relation to this case is unassessable.