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Consumer Product Safety

Incident Report

Subform I: General Information

1. Report Type.

New incident report

Incident Report Number: 2021-0084

2. Registrant Information.

Registrant Reference Number: M-129470-01-2

Registrant Name (Full Legal Name no abbreviations): Bayer CropScience Inc.

Address: Suite 200, 160 Quarry Park Blvd S.E.

City: Calgary

Prov / State: Alberta

Country: Canada

Postal Code: T2C 3G3

3. Select the appropriate subform(s) for the incident.

Scientific Study

4. Date registrant was first informed of the incident.

5. Location of incident.

6. Date incident was first observed.

Product Description

7. a) Provide the active ingredient and, if available, the registration number and product name (include all tank mixes). If the product is not registered provide a submission number.


PMRA Registration No.       PMRA Submission No.       EPA Registration No. Unknown

Product Name:

  • Active Ingredient(s)

7. b) Type of formulation.

Application Information

8. Product was applied?


9. Application Rate.

10. Site pesticide was applied to (select all that apply).

11. Provide any additional information regarding application (how it was applied, amount applied, the size of the area treated etc).

To be determined by Registrant

12. In your opinion, was the product used according to the label instructions?


Subform VII: Scientific Study

1. Study Reference

Title HOE 107892; SUBSTANCE, TECHNICAL(Code: Hoe 107892 00 ZC97 0001): Testing for acute intraperitoneal toxicityin the male and female Wistar rat

Date 11-FEB-91

2. a) Is an extension needed to translate the document?


3. Type of incident identified in the study

New health or environmental hazard

4. Describe the incident identified in the study (e.g. study demonstrates an increased risk to non-Hodgkin's Lymphoma after exposure to pesticide X)

Following intraperitoneal administration of 1000 mg/kg bw mefenpyr-diethyl, 2/5 male and 3/5 female rats died, and clinical signs of toxicity and necropsy findings were observed. Although the intraperitoneal route represents an unrealistic exposure scenario, the study is being submitted out of an abundance of caution. The effects by more typical routes of unintended exposure, oral and dermal, have been assessed and revealed low potential for toxicity. No deaths or necropsy findings were observed following oral or dermal treatment with mefenpyr-diethyl in rats at higher doses (5000 and 4000 mg/kg bw, respectively).

5. a) Was the study discontinued before completion?


5. b) Provide the reason for discontinuation

6. If the study is ongoing, what is the expected completion date?

For Registrant use only

7. Provide supplemental information here