New incident report
Incident Report Number: 2020-1513
Registrant Reference Number: USA-BAYERBAH-2020-US0017133 (Report 631911)
Registrant Name (Full Legal Name no abbreviations): Bayer inc
Address: 2920 Matheson Blvd
City: Mississaugua
Prov / State: ON
Country: Canada
Postal Code: L4W 5R6
Domestic Animal
Country: UNITED STATES
Prov / State: SOUTH CAROLINA
Unknown
PMRA Registration No. PMRA Submission No. EPA Registration No. 11556-155
Product Name: Seresto Cat
Other (specify)
COLLARYes
Other Units: COLLAR
Site: Animal / Usage sur un animal domestique
Animal's Owner
Cat / Chat
Domestic Shorthair
1
Male
11
Unknown
Skin
Unknown / Inconnu
Unknown / Inconnu
System
Unknown / Inconnu
No
No
Died
Treatment / Traitement
(eg. description of the frequency and severity of the symptoms
On an unspecified date in 2019, approximately 1 week post collar placement, the cat exhibited application site alopecia, behavior change, and vomiting. The owner removed the collar. On 05Mar2020 the cat died. It is unknown if a necropsy was preformed. No further information is expected. This case is closed.
Death
O - Unclassifiable/unassessable The reported application site alopecia may occur in sensitive animals after product application. It is usually mild and transient. Sign and time to onset are consistent. Behavioural change is unspecific and may have numerous other causes. Sign may occur initially after collar Administration, however time to onset rather Long here. Vomiting is unspecific and may have numerous other causes (e.g. gastrointestinal infection, dietary incompatibility). Though mild gastrointestinal signs may occur shortly after product application, they are not expected to appear with long time to onset. No oral product exposure reported. Death is not expected following appropriate topical product application as inconsistent with product's pharmacological profile. Oral exposure to the collar is not expected to cause serious signs either. An overdose of 5 collars around the neck was investigated in adult cats and dogs for an 8 months period and in 10 week old kittens and 7 week old puppies for a 6 months period without causing serious signs. This is supported by the extremely low systemic exposure with imidacloprid and flumethrin, particularly during the first week after application and also thereafter. Time to onset is long. Other causes must be considered in this geriatric cat (11 years). In summary, a product involvement is considered unassessable.