New incident report
Incident Report Number: 2019-6461
Registrant Reference Number: USA-BAYERBAH-2019-US0062398 (Report 605226)
Registrant Name (Full Legal Name no abbreviations): Bayer inc
Address: 2920 Matheson Blvd
City: Mississaugua
Prov / State: ON
Country: Canada
Postal Code: L4W 5R6
Domestic Animal
Country: UNITED STATES
Prov / State: OHIO
PMRA Registration No. 29777 PMRA Submission No. EPA Registration No.
Product Name: K9advantixII small dog
Other (specify)
spot-onYes
Units: mL
Site: Animal / Usage sur un animal domestique
Animal's Owner
Dog / Chien
Siberian Husky
1
Male
0.19
4.082
kg
Skin
>8 hrs <= 24 hrs / >8 h <= 24 h
>8 hrs <=24 hrs / > 8 h < = 24 h
System
Unknown / Inconnu
Yes
Yes
1
Day(s) / Jour(s)
Died
Treatment / Traitement
(eg. description of the frequency and severity of the symptoms
On 05-Oct-2019, the dog exhibited diarrhea. On 07-Oct-2019, the dog was evaluated and administered unspecified vaccinations by the veterinarian and started on a bland diet. On 08-Oct-2019, the diarrhea worsened. The dog then exhibited anorexia and intermittent vomiting. The dog was evaluated by an emergency veterinarian. The parvovirus test ran was negative, and the dog was administered unspecified amounts of subcutaneous fluids, maropitant, and metronidazole by the veterinarian. The dog was not hospitalized. On 09-Oct-2019, the dog exhibited lethargy. The dog was examined by a veterinarian who performed blood work, radiographs, and a fecal exam; all were within normal limits. The dog was administered an unspecified dose of fenbendazole and maropitant by the veterinarian. On 10-Oct-2019, the dog exhibited inappropriate urination and inappropriate defecation. The dog was evaluated by another emergency veterinarian, hospitalized, and administered intravenous fluids. On 11-Oct-2019, the dog collapsed and died. No necropsy was performed.
Death
Reported diarrhoea is an unspecific sign and may have many potential causes. Time to onset is consistent, however duration is exceptionally long. Dog was vaccinated and diet was changed, after which dog's condition deteriorated. Vomiting, lethargy, anorexia and later reported inappropriate urination and inappropriate defecation are unspecific signs. Collapse and death are not expected in dogs, as it is inconsistent with the pharmaco-toxicological profile of the product. Other causes should be considered, e.g. other products used, or congenital disorders. No necropsy performed. Onset time is rather long for later reported signs. In the end, a product connection for the case is unassessable.