Incident Report

Subform I: General Information

1. Report Type.

New incident report

Incident Report Number: 2019-6123

2. Registrant Information.

Registrant Reference Number: 190171450

Registrant Name (Full Legal Name no abbreviations): Wellmark International

Address: 100 Stone Road West, Suite 111

City: Guelph

Prov / State: Ontario

Country: Canada

Postal Code: N1G5L3

3. Select the appropriate subform(s) for the incident.

Domestic Animal

4. Date registrant was first informed of the incident.

28-SEP-19

5. Location of incident.

Country: UNITED STATES

Prov / State: MICHIGAN

6. Date incident was first observed.

28-SEP-19

Product Description

7. a) Provide the active ingredient and, if available, the registration number and product name (include all tank mixes). If the product is not registered provide a submission number.

Active(s)

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PMRA Registration No.       PMRA Submission No.       EPA Registration No. 2724-404

Product Name: Zodiac Fleatrol Flea And Tick Spray For Dogs Cats Puppies And Kittens

• Active Ingredient(s)
  • (S)-METHOPRENE
    • Guarantee/concentration .27 %
  • N-OCTYL BICYCLOHEPTENE DICARBOXIMIDE
    • Guarantee/concentration .62 %
  • PIPERONYL BUTOXIDE
    • Guarantee/concentration .37 %
  • PYRETHRINS
    • Guarantee/concentration .2 %

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7. b) Type of formulation.

Liquid

Application Information

8. Product was applied?

Yes

9. Application Rate.

Unknown

10. Site pesticide was applied to (select all that apply).

Site: Animal / Usage sur un animal domestique

11. Provide any additional information regarding application (how it was applied, amount applied, the size of the area treated etc).

On September 28, 2019, the owner applied the spray to the cat to treat a condition. It is unknown if the owner consulted with a veterinarian before using on the geriatric cat.

To be determined by Registrant

12. In your opinion, was the product used according to the label instructions?

Unknown

Subform III: Domestic Animal Incident Report

1. Source of Report

Animal's Owner

2. Type of animal affected

Cat / Chat

3. Breed

Manx

4. Number of animals affected

1

5. Sex

Male

6. Age (provide a range if necessary )

11.0

7. Weight (provide a range if necessary )

17.5

lbs

8. Route(s) of exposure

Skin

9. What was the length of exposure?

<=15 min / <=15 min

10. Time between exposure and onset of symptoms

<=30 min / <=30 min

11. List all symptoms

System

• Gastrointestinal System
  • Symptom - Salivating excessively

• Respiratory System
  • Symptom - Other
  • Specify - Abnormal Breathing

• General
  • Symptom - Pale mucous membrane colour
  • Symptom - Death

12. How long did the symptoms last?

Persisted until death

13. Was medical treatment provided? Provide details in question 17.

No

14. a) Was the animal hospitalized?

No

14. b) How long was the animal hospitalized?

15. Outcome of the incident

Died

16. How was the animal exposed?

Treatment / Traitement

17. Provide any additional details about the incident

(eg. description of the frequency and severity of the symptoms

Shortly after the product was applied on September 28, 2019, the cat developed hypersalivation and abnormal breathing. The owner then bathed the cat with Dawn dish soap. Soon after, the cat developed pale mucous membrane color. Thirty minutes later, the cat passed away. That afternoon, the owner contacted the Animal Product Safety Service (APSS). The APSS veterinarian stated that a taste reaction to the scent or taste of the agent, in some individuals may be seen. The APSS veterinarian also stated that severe flea anemia may trigger a fatal response if the cat was stressed by the spray, and that there may be some risk for an asthmatic reaction if inhaled. The APSS veterinarian recommended a necropsy, to have the veterinarian call for information, and to call back with questions.

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To be determined by Registrant

18. Severity classification (if there is more than 1 possible classification

Death

19. Provide supplemental information here

A necropsy was unavailable as the manufacturer declined to pursue a necropsy. It is unknown if the owner consulted a veterinarian before using the product on the geriatric cat.