New incident report
Incident Report Number: 2019-1309
Registrant Reference Number: USA-BAYERBAH-2019-US0005268 (Report 547759)
Registrant Name (Full Legal Name no abbreviations): Bayer inc
Address: 2920 Matheson Blvd
City: Mississaugua
Prov / State: ON
Country: Canada
Postal Code: L4W 5R6
Domestic Animal
Country: UNITED STATES
Prov / State: CONNECTICUT
PMRA Registration No. PMRA Submission No. EPA Registration No. 11556-155
Product Name: Seresto large dog
Other (specify)
COLLARYes
Other Units: COLLAR
Site: Animal / Usage sur un animal domestique
Animal's Owner
Dog / Chien
German Shepherd Dog
1
Male
1
31.75
kg
Skin
>3 days <=1 wk / >3 jours <=1 sem
>1 wk <=1 mo / > 1 sem < = 1 mois
System
Persisted until death
No
No
Died
Treatment / Traitement
(eg. description of the frequency and severity of the symptoms
On 26-Jan-2019, the collar was removed by the animal owner for an unknown reason. On 14-Feb-2019, the dog collapsed and died. The dog was evaluated by the veterinarian, however, no treatments or tests were performed. No necropsy was performed. The intent of the call was to inquire about product use in general and not to report this event.
Death
N - Unlikely Reported collapse and death are not expected following appropriate topical product application as inconsistent with product's pharmacological profile. Oral exposure to the collar is not expected to cause serious signs either. An overdose of 5 collars around the neck was investigated in adult cats and dogs for an 8 months period and in 10 week old kittens and 7 week old puppies for a 6 months period without causing serious signs. This is supported by the extremely low systemic exposure with imidacloprid and flumethrin, particularly during the first week after application and also thereafter. No signs of anaphylaxis reported which would have occurred in close proximity to the collar application. Moreover, signs were reported very long time after collar removal. Other unrelated causes are more probable. Finally, product involvement is considered unlikely.