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Consumer Product Safety

Incident Report

Subform I: General Information

1. Report Type.

New incident report

Incident Report Number: 2019-0764

2. Registrant Information.

Registrant Reference Number: 180167841

Registrant Name (Full Legal Name no abbreviations): Wellmark International

Address: 100 Stone Road West, Suite 111

City: Guelph

Prov / State: Ontario

Country: Canada

Postal Code: N1G5L3

3. Select the appropriate subform(s) for the incident.

Domestic Animal

4. Date registrant was first informed of the incident.

06-OCT-18

5. Location of incident.

Country: UNITED STATES

Prov / State: INDIANA

6. Date incident was first observed.

06-OCT-18

Product Description

7. a) Provide the active ingredient and, if available, the registration number and product name (include all tank mixes). If the product is not registered provide a submission number.

Active(s)

PMRA Registration No.       PMRA Submission No.       EPA Registration No. 2724-274

Product Name: Starbar Golden Malrin Fly Bait 1% Methomyl

  • Active Ingredient(s)
    • (Z)-9-TRICOSENE
      • Guarantee/concentration .049 %
    • METHOMYL
      • Guarantee/concentration 1 %

7. b) Type of formulation.

Bait

Application Information

8. Product was applied?

Yes

9. Application Rate.

Unknown

10. Site pesticide was applied to (select all that apply).

Site: Res. - Out Home / Rés - à l'ext.maison

11. Provide any additional information regarding application (how it was applied, amount applied, the size of the area treated etc).

At an unknown date and time, the owner inappropriately mixed this product with marshmallows and cola and put it outside to kill raccoons.

To be determined by Registrant

12. In your opinion, was the product used according to the label instructions?

No

Subform III: Domestic Animal Incident Report

1. Source of Report

Medical Professional

2. Type of animal affected

Dog / Chien

3. Breed

Australian Shepherd

4. Number of animals affected

1

5. Sex

Male

6. Age (provide a range if necessary )

0.5

7. Weight (provide a range if necessary )

40.0

lbs

8. Route(s) of exposure

Oral

9. What was the length of exposure?

>2 hrs <=8 hrs / >2 h <=8 h

10. Time between exposure and onset of symptoms

>30 min <=2 hrs / >30 min <=2 h

11. List all symptoms

System

  • Nervous and Muscular Systems
    • Symptom - Seizure
  • Respiratory System
    • Symptom - Apnea
  • Gastrointestinal System
    • Symptom - Salivating excessively
  • General
    • Symptom - Hyperthermia
  • Cardiovascular System
    • Symptom - Tachycardia
  • Gastrointestinal System
    • Symptom - Bloody diarrhea
  • General
    • Symptom - Death

12. How long did the symptoms last?

Persisted until death

13. Was medical treatment provided? Provide details in question 17.

Yes

14. a) Was the animal hospitalized?

Yes

14. b) How long was the animal hospitalized?

Unknown

15. Outcome of the incident

Died

16. How was the animal exposed?

Accidental ingestion/Ingestion accident.

17. Provide any additional details about the incident

(eg. description of the frequency and severity of the symptoms

On the morning of October 6, 2018, the dog ingested the marshmallow and product mixture. A little over a half an hour later, the dog developed seizures, apnea, and hypersalivation. The owner then took the dog to the regular veterinarian. The regular veterinarian noted the dog developed hyperthermia with a temperature of 108.0 degrees Fahrenheit (F) and tachycardia with a heart rate of 160.0 beats per minute. The regular veterinarian then provided fluid therapy, gave oxygen, midazolam, and butorphanol tartrate. The regular veterinarian then noted that the dog's temperature was normal, at 101.5 degrees F. Shortly after, the veterinary technician contacted the Animal Product Safety Service (APSS). The APSS veterinarian stated that methomyl is a carbamate insecticide with a narrow margin of safety and that clinical signs include muscarinic signs: salivation, lacrimation, urination, defecation, dyspnea (due to goblet cell secretions), and emesis (SLUDDE), miosis, and bradycardia. The APSS veterinarian also stated that nicotinic signs include tremors, twitching, weakness and paresis and that the onset is generally rapid. The APSS veterinarian continued by stating that if not a lethal exposure, signs are expected to resolve spontaneously due to the reversible nature of carbamate toxicity. Finally, the APSS veterinarian stated that atropine controls muscarinic signs (wet lung sounds and bradycardia) and that tremors and seizures can be treated with diazepam, oxygen as needed, and other symptomatic/supportive care. The APSS veterinarian recommended the regular veterinarian monitor heart rate, monitor for respiratory sounds (wet lung sounds), give atropine (if bradycardia or wet lungs), manage seizures (midazolam prn), give methocarbamol (if tremors), provide supportive care, provide symptomatic care, and to call back with questions. About thirty minutes later, the regular veterinary technician contacted the APSS to discuss the case. The regular veterinary technician stated that the dog had developed bloody diarrhea (frank blood, quite gelatinous). The APSS veterinarian recommended the regular veterinarian do a coagulation profile, a complete blood count (especially need platelet count), and to consider giving metronidazole due to the marked evidence of gut injury.


To be determined by Registrant

18. Severity classification (if there is more than 1 possible classification

Death

19. Provide supplemental information here

On October 8, 2018, an APSS assistant contacted the regular veterinarian to follow up on the case. The regular veterinary technician stated that the dog passed away on October 6, 2018 on the way to the emergency clinic. At the time of this report, a necropsy is not pending. This was off label use, as the bait should not be anywhere that pets may have access to it.