Health Canada
Symbol of the Government of Canada
Consumer Product Safety

Incident Report

Subform I: General Information

1. Report Type.

New incident report

Incident Report Number: 2018-6937

2. Registrant Information.

Registrant Reference Number: 180160650

Registrant Name (Full Legal Name no abbreviations): Wellmark International

Address: 100 Stone Road West, Suite 111

City: Guelph

Prov / State: Ontario

Country: Canada

Postal Code: N1G5L3

3. Select the appropriate subform(s) for the incident.

Domestic Animal

4. Date registrant was first informed of the incident.

23-SEP-18

5. Location of incident.

Country: CANADA

Prov / State: BRITISH COLUMBIA

6. Date incident was first observed.

21-SEP-18

Product Description

7. a) Provide the active ingredient and, if available, the registration number and product name (include all tank mixes). If the product is not registered provide a submission number.

Active(s)

PMRA Registration No. 31367      PMRA Submission No.       EPA Registration No.

Product Name: Zodiac Powerspot Flea And Tick Control For Dogs Under 14 kg (30 lbs)

  • Active Ingredient(s)
    • (S)-METHOPRENE
    • PERMETHRIN

7. b) Type of formulation.

Application Information

8. Product was applied?

Yes

9. Application Rate.

1

Units: mL

10. Site pesticide was applied to (select all that apply).

Site: Animal / Usage sur un animal domestique

11. Provide any additional information regarding application (how it was applied, amount applied, the size of the area treated etc).

On September 21, 2018, the owner inappropriately applied the dog product to the cat to treat a condition.

To be determined by Registrant

12. In your opinion, was the product used according to the label instructions?

No

Subform III: Domestic Animal Incident Report

1. Source of Report

Animal's Owner

2. Type of animal affected

Cat / Chat

3. Breed

Ragdoll

4. Number of animals affected

1

5. Sex

Female

6. Age (provide a range if necessary )

1.0

7. Weight (provide a range if necessary )

9.0

lbs

8. Route(s) of exposure

Skin

9. What was the length of exposure?

<=15 min / <=15 min

10. Time between exposure and onset of symptoms

>30 min <=2 hrs / >30 min <=2 h

11. List all symptoms

System

  • Skin
    • Symptom - Irritated skin
    • Specify - Application Site Irritation
  • General
    • Symptom - Lethargy
  • Nervous and Muscular Systems
    • Symptom - Fasciculations
  • Skin
    • Symptom - Erythema

12. How long did the symptoms last?

Unknown / Inconnu

13. Was medical treatment provided? Provide details in question 17.

Yes

14. a) Was the animal hospitalized?

Unknown

14. b) How long was the animal hospitalized?

15. Outcome of the incident

Unknown/Inconnu

16. How was the animal exposed?

Treatment / Traitement

17. Provide any additional details about the incident

(eg. description of the frequency and severity of the symptoms

Five minutes after the product was applied on September 21, 2018, the owner bathed the cat two times with cat shampoo. About an hour later, the cat developed application site irritation. On the morning of September 22, 2018, the cat developed lethargy. In the evening on September 23, 2018, the cat developed fasciculations. The owner then took the cat to the emergency veterinarian and contacted the Animal Product Safety Service (APSS). The APSS veterinarian stated that cats do not tolerate permethrin and that there are some individual variations in sensitivity. The APSS veterinarian also stated that signs range from mild paresthesia, ataxia, and tremors to seizures and that signs can develop from almost immediately up to 72 hours post-exposure. The APSS assistant recommended the owner have the veterinarian call for information. In the early morning on September 24, 2018, the emergency veterinarian contacted the APSS to continue the case. The emergency veterinarian stated that midazolam (diazepam) was given for the fasciculations. The emergency veterinarian also stated that the cat had developed erythema at the application site. The APSS veterinarian recommended the emergency veterinarian bathe the cat (if the application site is still greasy), applying vitamin E (to the application site), provide fluid therapy, give methocarbamol (Methocarbamol (Robaxin-V, Fort Dodge, 100 milligrams per milliliter (mg/ml), 20 milliliter (ml), or 100 ml vial): cats 55 to 220 milligrams per kilogram (mg/kg) intravenous (IV) for severe tremor/seizure activity, give 1/2 rapidly (not exceeding 2 milliliters per minute (ml/min)), allow the animal to relax, and then give to effect (repeat to max 330 milligrams per kilogram per day (mg/kg/day)). If the cat's fasciculations are too severe for IV placement, try methocarbamol rectally first at 100 mg/kg.), provide nutritional support, provide symptomatic care, provide supportive care, and to call back with questions.


To be determined by Registrant

18. Severity classification (if there is more than 1 possible classification

Moderate

19. Provide supplemental information here

This was off label use of the product, cats should not be treated with dog topicals.