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Consumer Product Safety

Incident Report

Subform I: General Information

1. Report Type.

New incident report

Incident Report Number: 2018-6153

2. Registrant Information.

Registrant Reference Number: 180136968

Registrant Name (Full Legal Name no abbreviations): Wellmark International

Address: 100 Stone Road West, Suite 111

City: Guelph

Prov / State: Ontario

Country: Canada

Postal Code: N1G5L3

3. Select the appropriate subform(s) for the incident.

Domestic Animal

4. Date registrant was first informed of the incident.

13-AUG-18

5. Location of incident.

Country: UNITED STATES

Prov / State: CALIFORNIA

6. Date incident was first observed.

13-AUG-18

Product Description

7. a) Provide the active ingredient and, if available, the registration number and product name (include all tank mixes). If the product is not registered provide a submission number.

Active(s)

PMRA Registration No.       PMRA Submission No.       EPA Registration No. 2724-274

Product Name: Starbar Golden Malrin Fly Bait 1% Methomyl

  • Active Ingredient(s)
    • (Z)-9-TRICOSENE
      • Guarantee/concentration .049 %
    • METHOMYL
      • Guarantee/concentration 1 %

7. b) Type of formulation.

Bait

Application Information

8. Product was applied?

Unknown

9. Application Rate.

10. Site pesticide was applied to (select all that apply).

11. Provide any additional information regarding application (how it was applied, amount applied, the size of the area treated etc).

To be determined by Registrant

12. In your opinion, was the product used according to the label instructions?

Unknown

Subform III: Domestic Animal Incident Report

1. Source of Report

Medical Professional

2. Type of animal affected

Dog / Chien

3. Breed

German Shepherd

4. Number of animals affected

1

5. Sex

Male

6. Age (provide a range if necessary )

0.27

7. Weight (provide a range if necessary )

35.0

lbs

8. Route(s) of exposure

Oral

9. What was the length of exposure?

Unknown / Inconnu

10. Time between exposure and onset of symptoms

Unknown / Inconnu

11. List all symptoms

System

  • Nervous and Muscular Systems
    • Symptom - Unresponsive
    • Symptom - Recumbent
  • General
    • Symptom - Lethargy
  • Respiratory System
    • Symptom - Dyspnea
  • Cardiovascular System
    • Symptom - Bradycardia
  • Gastrointestinal System
    • Symptom - Vomiting
  • General
    • Symptom - Death

12. How long did the symptoms last?

Persisted until death

13. Was medical treatment provided? Provide details in question 17.

Yes

14. a) Was the animal hospitalized?

Yes

14. b) How long was the animal hospitalized?

1.75

Hour(s) / Heure(s)

15. Outcome of the incident

Died

16. How was the animal exposed?

Accidental ingestion/Ingestion accident.

17. Provide any additional details about the incident

(eg. description of the frequency and severity of the symptoms

Sometime between August 12, 2018 and August 13, 2018, the dog ingested an unknown amount of this bait. In the afternoon on August 13, 2018, the dog was unresponsive and the owner took the dog to the regular veterinarian who gave a dose of epinephrine. The dog was recumbent and developed lethargy, dyspnea, and bradycardia. The regular veterinarian then contacted the Animal Product Safety Service (APSS). The regular veterinarian stated that the owner may have given the dog salt prior to coming to the clinic. The APSS veterinarian stated that methomyl is a carbamate that is rapidly absorbed after ingestion, but does not accumulate in the tissues and that it does not "age" on the receptors like organophosphates (OP's) do, so signs are often short-lived. The APSS veterinarian also stated that signs occur within minutes after ingestion, and include salivation, lacrimation, urination, diarrhea, dyspnea, and emesis (SLUDDE) signs, bradycardia, ataxia, weakness, tremors, seizures, and possibly death. The APSS veterinarian continued by stating that if not a lethal exposure, signs are expected to resolve spontaneously due to the reversible nature of carbamate toxicity and that death may occur due to severe bronchial secretions or seizures. The APSS veterinarian also stated that sodium chloride (table salt) can lead to signs of vomiting, polydipsia, potentially hypernatremia, and central nervous system (CNS) signs. The APSS veterinarian further stated that salt toxicity results in ataxia, tremors, and possibly seizures, and if left untreated can cause cerebral edema and potentially death. A few minutes after starting the call, the dog developed vomiting (there was bait in the vomitus). The APSS veterinarian recommended the regular veterinarian give atropine to control muscarinic signs. The dose can be repeated as needed, but do not over-atropinize the animal. The primary goal of atropine use is to control bradycardia and bronchial secretions. The APSS veterinarian also recommended the regular veterinarian manage vomiting, provide fluid therapy, monitor electrolytes for hypernatremia from the salt, monitor for gastrointestinal (GI) signs, monitor for respiratory signs, monitor cardiovascular function, give diazepam (or midazolam for tremors/seizures), give methocarbamol (for tremors), provide supportive care, provide symptomatic care, and to call back with questions.


To be determined by Registrant

18. Severity classification (if there is more than 1 possible classification

Death

19. Provide supplemental information here

On August 16, 2018, the regular veterinarian called to update the case. The regular veterinarian stated that the dog passed away soon after ending the call on August 13, 2018. At the time of this report, a necropsy was not pending. This product is not to be used where the dogs or livestock can be exposed to it.