New incident report
Incident Report Number: 2018-5513
Registrant Reference Number: USA-BAYERBAH-2018-US0051979 (Report 518176)
Registrant Name (Full Legal Name no abbreviations): Bayer inc
Address: 2920 Matheson BLVD
City: Mississaugua
Prov / State: ON
Country: Canada
Postal Code: L5W5R6
Domestic Animal
Country: UNITED STATES
Prov / State: PENNSYLVANIA
PMRA Registration No. PMRA Submission No. EPA Registration No. 11556-155
Product Name: Seresto Cat
Other (specify)
COLLARYes
Other Units: collar
Site: Animal / Usage sur un animal domestique
Animal's Owner
Cat / Chat
Domestic Longhair
1
Male
1
4.08
kg
Skin
>1 wk <=1 mo / > 1 sem < = 1 mois
>1 wk <=1 mo / > 1 sem < = 1 mois
System
Persisted until death
No
No
Died
Treatment / Traitement
(eg. description of the frequency and severity of the symptoms
On approximately 01-Sep-2018, the cat exhibited lethargy and anorexia. Approximately 4 hours post onset, the cat fell from a chair then exhibited recumbency, was unable to stand, vomited once, had apnea and died. No known necropsy was performed.
Death
N - Unlikely Reported systemic signs such as lethargy and anorexia are unspecific and may have numerous other causes. Neurological signs are not typically seen with appropriate topical product administration. No oral product exposure reported. Even with oral product exposure which was not reported only transient gastrointestinal signs are expected. Vomiting is unspecific either and may have multiple other causes (e.g. gastrointestinal infection, dietary incompatibility). Reported recumbancy, apnoea and death are not expected following appropriate topical product application as inconsistent with product's pharmacological profile. An overdose of 5 collars around the neck was investigated in adult cats and dogs for an 8 months period and in 10 week old kittens and 7 week old puppies for a 6 months period without causing serious sign. Product has wide margin of safety. In this case cat had felt from the chair which likely contributed to the later reported signs. Time to onset is long. Even though no necropsy was performed, considering all aspects, a product relation is unlikely.