Incident Report

Subform I: General Information

1. Report Type.

New incident report

Incident Report Number: 2017-7028

2. Registrant Information.

Registrant Reference Number: 170125796

Registrant Name (Full Legal Name no abbreviations): Wellmark International

Address: 100 Stone Road West, Suite 111

City: Guelph

Prov / State: Ontario

Country: Canada

Postal Code: N1G5L3

3. Select the appropriate subform(s) for the incident.

Domestic Animal

4. Date registrant was first informed of the incident.

23-JUL-17

5. Location of incident.

Country: CANADA

Prov / State: ONTARIO

6. Date incident was first observed.

23-JUL-17

Product Description

7. a) Provide the active ingredient and, if available, the registration number and product name (include all tank mixes). If the product is not registered provide a submission number.

Active(s)

---

PMRA Registration No. 21744      PMRA Submission No.       EPA Registration No.

Product Name: Zodiac Flea and Tick Spray For Dogs and Cats

• Active Ingredient(s)
  • (S)-METHOPRENE
  • N-OCTYL BICYCLOHEPTENE DICARBOXIMIDE
  • PIPERONYL BUTOXIDE
  • PYRETHRINS

---

7. b) Type of formulation.

Application Information

8. Product was applied?

Yes

9. Application Rate.

Unknown

10. Site pesticide was applied to (select all that apply).

Site: Animal / Usage sur un animal domestique

11. Provide any additional information regarding application (how it was applied, amount applied, the size of the area treated etc).

On July 23, 2017 the owner sprayed the cat 6-8 times with the product to treat for fleas.

To be determined by Registrant

12. In your opinion, was the product used according to the label instructions?

Unknown

Subform III: Domestic Animal Incident Report

1. Source of Report

Other

2. Type of animal affected

Cat / Chat

3. Breed

Persian

4. Number of animals affected

1

5. Sex

Female

6. Age (provide a range if necessary )

0.42

7. Weight (provide a range if necessary )

4.0

lbs

8. Route(s) of exposure

Skin

Oral

9. What was the length of exposure?

<=15 min / <=15 min

10. Time between exposure and onset of symptoms

<=30 min / <=30 min

11. List all symptoms

System

• Gastrointestinal System
  • Symptom - Salivating excessively

• General
  • Symptom - Lethargy

12. How long did the symptoms last?

Unknown / Inconnu

13. Was medical treatment provided? Provide details in question 17.

Unknown

14. a) Was the animal hospitalized?

Unknown

14. b) How long was the animal hospitalized?

15. Outcome of the incident

Unknown/Inconnu

16. How was the animal exposed?

Treatment / Traitement

17. Provide any additional details about the incident

(eg. description of the frequency and severity of the symptoms

Shortly after applying the product, the cat developed hypersalivation. A few minutes later, the owner bathed the cat (first rinsed with water and then gave another bath with cat shampoo). Sometime before or after the bath, the cat developed lethargy (the owner is unsure of when the lethargy first started). The cat has been licking herself after the baths. About an hour later, an extended family member contacted the Animal Product Safety Service (APSS). The APSS veterinarian stated that the risk is for oral symptoms. The APSS technician recommended the owner monitor at home, bathe the cat (recommended bathing the animal with a liquid dish washing detergent like Dawn or Palmolive, repeat baths until product has been significantly decreased or eliminated, rinse the pet thoroughly and dry with a towel or blow dryer), give a taste treat (offer the pet tuna juice or canned cat food now), monitor for lethargy (if lethargy is more than mild or persists, take the pet into a veterinary clinic), monitor for gastrointestinal (GI) signs (monitor for drooling or vomiting, if more than mild, call back), call a veterinarian (recommended caller follow up with the pet's regular veterinarian (rDVM) to discuss using a different flea medication), discontinue product usage (recommended using a different product with different active ingredients), manage vomiting (nothing by mouth (NPO) for one hour, reintroduce water slowly, if no vomiting, reintroduce food), call back with questions (if GI upset is more than mild), take the animal to a veterinarian (if lethargy is persistent), and have the veterinarian call for information.

---

To be determined by Registrant

18. Severity classification (if there is more than 1 possible classification

Minor

19. Provide supplemental information here

The signs were expected to be mild and self-limiting.