New incident report
Incident Report Number: 2017-4012
Registrant Reference Number: USA-BAYERBAH-2017-US0019270
Registrant Name (Full Legal Name no abbreviations): Bayer inc
Address: 2920 Matheson Blvd
City: Mississaugua
Prov / State: ON
Country: Canada
Postal Code: L4W 5R6
Domestic Animal
Country: UNITED STATES
Prov / State: NEW JERSEY
PMRA Registration No. PMRA Submission No. EPA Registration No. Unknown
Product Name: advantage II pipette size unknown
Other (specify)
spot-onYes
Unknown
Site: Animal / Usage sur un animal domestique
Unknown
Animal's Owner
Cat / Chat
Unknown
1
Unknown
17
Unknown
Skin
Unknown / Inconnu
>2 mos <=6 mos / > 2 mois < = 6 mois
System
Unknown / Inconnu
Unknown
Unknown
Died
Treatment / Traitement
(eg. description of the frequency and severity of the symptoms
On approximately 01-May-2015, a 17 year old feline, of unknown signalment, in unknown condition, with no known concomitant medical conditions, was administered 1 tube of Advantage II (cat-unspecified) (Imidacloprid-Pyriproxyfen) topically by the owner. On approximately 01-Sep-2016, the cat died and no necropsy was performed. Due to the sensitive nature of the communication, specific relevant event details were not obtained, nor will such be sought. The reason for the initial call was to discuss the use of the product and not to report the death of the patient. No further information is expected. This case is closed.
Death
N - Unlikely Death is inconsistent with pharmaco-toxicological product profile and experience. Product has wide margin of safety. Oral LD50 in rat is 642 mg/kg BW. 24-fold overdosage tolerated by cats without showing any side effect. Time to onset is long. Other causes are more probable in this geriatric cat. Moreover, the reason for the initial call was to discuss the use of the product and not to report the death of the patient. Even though some information missing (Animal health status and necropsy report), considering products known safety profile, product involvement is deemed to be unlikely.