New incident report
Incident Report Number: 2017-0578
Registrant Reference Number: 2017KP081
Registrant Name (Full Legal Name no abbreviations): Bayer Inc
Address: 2920 matheson BLVD
City: Mississaugua
Prov / State: ON
Country: Canada
Postal Code: L4W 5R6
Domestic Animal
Country: UNITED STATES
Prov / State: UNKNOWN
Unknown
PMRA Registration No. PMRA Submission No. EPA Registration No. 11556-155
Product Name: Seresto Collar - Cat
Other (specify)
collarYes
Other Units: collar
Site: Animal / Usage sur un animal domestique
Other
Cat / Chat
Unknown
1
Male
12
Unknown
Skin
>1 wk <=1 mo / > 1 sem < = 1 mois
Unknown / Inconnu
System
Unknown / Inconnu
Yes
No
Died
Treatment / Traitement
(eg. description of the frequency and severity of the symptoms
On an unspecified date in May-2016, the cat exhibited intermittent vomiting. On an unspecified date in Jun-2016, the cat exhibited a constipation and was examined by a veterinarian. Radiographs were performed and the cat was diagnosed with a partial intestinal obstruction. On an unspecified date in Aug-2016, the cat was diagnosed with multiple organ failure. On 27-Aug-2016, the cat was examined by an emergency veterinarian, went into cardiac arrest, and died. No necropsy was performed. Due to the sensitive nature of the communication, specific relevant event details were not obtained, nor will such be sought. The reason for the initial phone call was to expiration date not to report the death of the patient. No further information is expected. Case is closed.
Death
Vomiting is unspecific and may have numerous other causes (e.g. gastrointestinal infection, dietary incompatibility). Mild gastrointestinal signs may occur shortly after product application, however, time to onset of sign is unknown. No oral product exposure reported. Constipation is not anticipated with appropriate topical product administration. In this case it is likely associated with the later diagnosed partial intestinal obstruction. The reported serious signs like multiple organ failure, cardiac arrest and death are not expected following appropriate topical product application as inconsistent with products pharmacological profile. Time to onset is unknown, however, seems long. Oral exposure to the collar is not expected to cause such signs either. An overdose of 5 collars around the neck was investigated in adult cats and dogs for an 8 months period and in 10 week old kittens and 7 week old puppies for a 6 months period without causing serious signs. Moreover, the reason for the initial phone call was to ask for expiration date and not to report the death of the patient. Animal involved in this case was geriatric which may have further contributed the signs. Even though some information is not available (health status, medical history, time to onset and necropsy report), sufficient information exists to rule out product relation completely. Overall, a product relation is considered as unlikely.