Incident Report

Subform I: General Information

1. Report Type.

New incident report

Incident Report Number: 2014-6158

2. Registrant Information.

Registrant Reference Number: 140117456

Registrant Name (Full Legal Name no abbreviations): Wellmark International

Address: 100 Stone Road West, Suite 111

City: Guelph

Prov / State: Ontario

Country: Canada

Postal Code: N1G5L3

3. Select the appropriate subform(s) for the incident.

Domestic Animal

4. Date registrant was first informed of the incident.

15-SEP-14

5. Location of incident.

Country: CANADA

Prov / State: ONTARIO

6. Date incident was first observed.

15-SEP-14

Product Description

7. a) Provide the active ingredient and, if available, the registration number and product name (include all tank mixes). If the product is not registered provide a submission number.

Active(s)

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PMRA Registration No. 21744      PMRA Submission No.       EPA Registration No.

Product Name: Zodiac Flea and Tick Spray for Dogs and Cats

• Active Ingredient(s)
  • (S)-METHOPRENE
  • N-OCTYL BICYCLOHEPTENE DICARBOXIMIDE
  • PIPERONYL BUTOXIDE
  • PYRETHRINS

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7. b) Type of formulation.

Application Information

8. Product was applied?

Yes

9. Application Rate.

Unknown

10. Site pesticide was applied to (select all that apply).

Site: Animal / Usage sur un animal domestique

11. Provide any additional information regarding application (how it was applied, amount applied, the size of the area treated etc).

On September 15, 2014 the owner applied the product onto the cat to treat for fleas.

To be determined by Registrant

12. In your opinion, was the product used according to the label instructions?

Unknown

Subform III: Domestic Animal Incident Report

1. Source of Report

Animal's Owner

2. Type of animal affected

Cat / Chat

3. Breed

Persian

4. Number of animals affected

1

5. Sex

Male

6. Age (provide a range if necessary )

8.5

7. Weight (provide a range if necessary )

10.0

lbs

8. Route(s) of exposure

Skin

9. What was the length of exposure?

Unknown / Inconnu

10. Time between exposure and onset of symptoms

>2 hrs <=8 hrs / > 2 h < = 8 h

11. List all symptoms

System

• General
  • Symptom - Lethargy
  • Symptom - Hesitancy to move

• Nervous and Muscular Systems
  • Symptom - Muscle tremors

12. How long did the symptoms last?

Unknown / Inconnu

13. Was medical treatment provided? Provide details in question 17.

Yes

14. a) Was the animal hospitalized?

Yes

14. b) How long was the animal hospitalized?

9.5

Hour(s) / Heure(s)

15. Outcome of the incident

Not recovered / Non rétabli

16. How was the animal exposed?

Treatment / Traitement

17. Provide any additional details about the incident

(eg. description of the frequency and severity of the symptoms

On September 15, 2014 the owner noticed the cat was lethargic and hesitant to move, so the owner contacted the Animal Product Safety Service. The APSS veterinarian stated would not really expect signs like this, although sometimes cats can act oddly when treated with this. The APSS veterinarian further stated this seems worse than I would expect and it would be best to have him examined. The APSS assistant recommended bathing the cat with liquid dish washing detergent (LDWD), monitoring the cat at home, and taking the cat to the veterinarian (if symptoms persist for one hour after bathing).

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To be determined by Registrant

18. Severity classification (if there is more than 1 possible classification

Moderate

19. Provide supplemental information here

On September 18, 2014 the owner called the APSS back to update the case. The owner stated she bathed the cat with LDWD. The cat's signs continued and tremors developed so the owner took the cat to the veterinarian, where they administered methocarbamol. On September 16, 2014 the cat's tremors resolved and the cat was discharged from the veterinary clinic. The owner stated more methocarbamol was sent home, but she was instructed not to use it. The cat is still lethargic and hesitant to move. The APSS veterinarian stated with the active ingredients having been confirmed, we wouldn't expect to see this kind of reaction from the product, unless he was severely sensitive to pyrethrins. The APSS technician recommended having the veterinarian to call for information and discussed the possibility of the cat coming in contact with a dog that had been treated with a permethrin product. The owner stated the cat hasn't come into contact with any dogs.