Incident Report

Subform I: General Information

1. Report Type.

New incident report

Incident Report Number: 2014-6127

2. Registrant Information.

Registrant Reference Number: 140136479

Registrant Name (Full Legal Name no abbreviations): Wellmark International

Address: 100 Stone Road West, Suite 111

City: Guelph

Prov / State: Ontario

Country: Canada

Postal Code: N1G5L3

3. Select the appropriate subform(s) for the incident.

Domestic Animal

4. Date registrant was first informed of the incident.

27-OCT-14

5. Location of incident.

Country: CANADA

Prov / State: ONTARIO

6. Date incident was first observed.

27-OCT-14

Product Description

7. a) Provide the active ingredient and, if available, the registration number and product name (include all tank mixes). If the product is not registered provide a submission number.

Active(s)

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PMRA Registration No. 26493      PMRA Submission No.       EPA Registration No.

Product Name: Zodiac Powerspot Flea And Tick Control For Dogs Over 14 kg (30 lbs)

• Active Ingredient(s)
  • (S)-METHOPRENE
  • PERMETHRIN

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7. b) Type of formulation.

Application Information

8. Product was applied?

Yes

9. Application Rate.

Unknown

10. Site pesticide was applied to (select all that apply).

Site: Animal / Usage sur un animal domestique

11. Provide any additional information regarding application (how it was applied, amount applied, the size of the area treated etc).

On October 27, 2014 the owner inappropriately applied 2 drops of the dog product to the back of the cat's head.

To be determined by Registrant

12. In your opinion, was the product used according to the label instructions?

No

Subform III: Domestic Animal Incident Report

1. Source of Report

Medical Professional

2. Type of animal affected

Cat / Chat

3. Breed

Domestic Longhair

4. Number of animals affected

1

5. Sex

Male

6. Age (provide a range if necessary )

2.0

7. Weight (provide a range if necessary )

5.6

kg

8. Route(s) of exposure

Skin

Oral

9. What was the length of exposure?

>15 min <=2 hrs / >15 min <=2 h

10. Time between exposure and onset of symptoms

>30 min <=2 hrs / >30 min <=2 h

11. List all symptoms

System

• General
  • Symptom - Hyperactivity

• Respiratory System
  • Symptom - Panting

• Cardiovascular System
  • Symptom - Tachycardia

12. How long did the symptoms last?

Unknown / Inconnu

13. Was medical treatment provided? Provide details in question 17.

Yes

14. a) Was the animal hospitalized?

Unknown

14. b) How long was the animal hospitalized?

15. Outcome of the incident

Unknown/Inconnu

16. How was the animal exposed?

Treatment / Traitement

17. Provide any additional details about the incident

(eg. description of the frequency and severity of the symptoms

On October 27, 2014 the cat became symptomatic so was taken to the veterinary clinic where they bathed him using liquid dish washing detergent (LDWD). The attending veterinarian then contacted the Animal Product Safety Service (APSS). The APSS veterinarian stated there is risk for life threatening signs anytime a dog product containing permethrins is applied to a cat as cats are very sensitive to this chemical. The APSS veterinarian also stated there is risk for gastrointestinal (GI) upset, lethargy, ataxia, depression, anorexia, tremors, seizures, and death. The APSS veterinarian finally stated with this being a small amount applied and then it was washed off in a short amount of time the risk for signs should be low. The APSS veterinarian recommended monitoring the cat at the veterinary facility for GI and central nervous system (CNS) signs, giving fluid therapy, monitoring body temperature, and giving methocarbamol (50-220 milligrams per kilogram (mg/kg) intravenously (IV) slow for tremors or seizures).

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To be determined by Registrant

18. Severity classification (if there is more than 1 possible classification

Moderate

19. Provide supplemental information here

The APSS veterinarian stated that the substance was considered to have a low likelihood of causing the clinical situation. Multiple attempts to update the case were unsuccessful; therefore, the outcome is unknown. Off label use: dog product not labelled for use on cats.