Health Canada
Symbol of the Government of Canada
Consumer Product Safety

Incident Report

Subform I: General Information

1. Report Type.

New incident report

Incident Report Number: 2014-1514

2. Registrant Information.

Registrant Reference Number: 140009596

Registrant Name (Full Legal Name no abbreviations): Wellmark International

Address: 100 Stone Road West, Suite 111

City: Guelph

Prov / State: Ontario

Country: Canada

Postal Code: N1G5L3

3. Select the appropriate subform(s) for the incident.

Domestic Animal

4. Date registrant was first informed of the incident.

24-JAN-14

5. Location of incident.

Country: CANADA

Prov / State: QUEBEC

6. Date incident was first observed.

22-JAN-14

Product Description

7. a) Provide the active ingredient and, if available, the registration number and product name (include all tank mixes). If the product is not registered provide a submission number.

Active(s)

PMRA Registration No. 21206      PMRA Submission No.       EPA Registration No.

Product Name: Vet Kem Ovitrol Plus For Dogs and Cats (Canadian)

  • Active Ingredient(s)
    • (S)-METHOPRENE
    • N-OCTYL BICYCLOHEPTENE DICARBOXIMIDE
    • PIPERONYL BUTOXIDE
    • PYRETHRINS

7. b) Type of formulation.

Application Information

8. Product was applied?

Yes

9. Application Rate.

Unknown

10. Site pesticide was applied to (select all that apply).

Site: Animal / Usage sur un animal domestique

11. Provide any additional information regarding application (how it was applied, amount applied, the size of the area treated etc).

On January 22, 2014 the owner applied the product to the adult cats in the house, one a lactating female.

To be determined by Registrant

12. In your opinion, was the product used according to the label instructions?

Unknown

Subform III: Domestic Animal Incident Report

1. Source of Report

Medical Professional

2. Type of animal affected

Cat / Chat

3. Breed

Domestic Unspecified

4. Number of animals affected

1

5. Sex

Female

6. Age (provide a range if necessary )

2.0

7. Weight (provide a range if necessary )

Unknown

8. Route(s) of exposure

Skin

9. What was the length of exposure?

Unknown / Inconnu

10. Time between exposure and onset of symptoms

>2 hrs <=8 hrs / > 2 h < = 8 h

11. List all symptoms

System

  • General
    • Symptom - Lethargy
    • Symptom - Dehydration
    • Symptom - Death

12. How long did the symptoms last?

Persisted until death

13. Was medical treatment provided? Provide details in question 17.

Unknown

14. a) Was the animal hospitalized?

Unknown

14. b) How long was the animal hospitalized?

15. Outcome of the incident

Died

16. How was the animal exposed?

Treatment / Traitement

17. Provide any additional details about the incident

(eg. description of the frequency and severity of the symptoms

On January 22, 2014 the owner noticed the cat was lethargic. On January 24, 2014 the owner took the cat to the regular veterinarian where they stated the cat was dehydrated. Shortly after, the veterinary technician called the Animal Product Safety Service (APSS) to obtain help. The APSS veterinarian stated death is not expected. The APSS veterinarian recommended bathing the cat, providing fluid therapy, symptomatic and supportive care, and call back with questions. The owner refused fluid therapy due to finances. The veterinary technician also inquired about reimbursement for the care of the cat. The APSS veterinarian referred the veterinary technician back to the manufacturer to discuss assistance with treatment of the cat.


To be determined by Registrant

18. Severity classification (if there is more than 1 possible classification

Death

19. Provide supplemental information here

The APSS veterinarian stated that the substance was considered to have a doubtful likelihood of causing the clinical situation. On January 28, 2014 the veterinary technician called the APSS to let us know several of the cats had died and was inquiring about necropsy submission. Necropsy results are pending. Unknown if veterinarian was consulted before application on lactating female.

Subform III: Domestic Animal Incident Report

1. Source of Report

Medical Professional

2. Type of animal affected

Cat / Chat

3. Breed

Domestic Shorthair

4. Number of animals affected

1

5. Sex

Male

6. Age (provide a range if necessary )

1.5

7. Weight (provide a range if necessary )

Unknown

8. Route(s) of exposure

Skin

9. What was the length of exposure?

Unknown / Inconnu

10. Time between exposure and onset of symptoms

>2 hrs <=8 hrs / > 2 h < = 8 h

11. List all symptoms

System

  • General
    • Symptom - Lethargy
    • Symptom - Dehydration
    • Symptom - Death

12. How long did the symptoms last?

Persisted until death

13. Was medical treatment provided? Provide details in question 17.

Unknown

14. a) Was the animal hospitalized?

Unknown

14. b) How long was the animal hospitalized?

15. Outcome of the incident

Died

16. How was the animal exposed?

Treatment / Traitement

17. Provide any additional details about the incident

(eg. description of the frequency and severity of the symptoms

On January 22, 2014 the owner noticed the cat was lethargic. On January 24, 2014 the owner took the cat to the regular veterinarian where they stated the cat was dehydrated. Shortly after, the veterinary technician called the Animal Product Safety Service (APSS) to obtain help.The APSS veterinarian stated death is not expected. The APSS veterinarian recommended bathing the cat, providing fluid therapy, symptomatic and supportive care, and call back with questions. The owner refused fluid therapy due to finances. The veterinary technician also inquired about reimbursement for the care of the cat. The APSS veterinarian referred the veterinary technician back to the manufacturer to discuss assistance with treatment of the cat.


To be determined by Registrant

18. Severity classification (if there is more than 1 possible classification

Death

19. Provide supplemental information here

The APSS veterinarian stated that the substance was considered to have a doubtful likelihood of causing the clinical situation. On January 26 and 28, 2014 several attempts to follow-up the case were attempted. On January 28, 2014 the veterinary technician called the APSS to let us know several of the cats had died and was inquiring about necropsy submission. On April 22, 2014 the APSS diagnostic technican received the necropsy results which reported severe necrotizing pneumonia with fibrinosupportive pleauritis and enteritis with crypt necrosis, compatible with feline parvovirus/panleukopenia. In summary, the cause of death of this cat is a severe pneumonia with pleuritis, in combination with panleukopenia. Toxicology testing for permethrins was inconclusive, meaning exposure could neither be confirmed or ruled out, due to analytical technical difficulties. The APSS veterinarian stated that pneumonia was considered to have a high likelihood of causing the clinical situation. The APSS veterinarian stated that feline parvovirus or feline panleukopenia were considered to have a high likelihood of causing the clinical situation.