New incident report
Incident Report Number: 2013-1011
Registrant Reference Number: 120111710
Registrant Name (Full Legal Name no abbreviations): Wellmark International
Address: 100 Stone Road West, Suite 111
City: Guelph
Prov / State: Ontario
Country: Canada
Postal Code: N1G5L3
Domestic Animal
Country: UNITED STATES
Prov / State: GEORGIA
PMRA Registration No. PMRA Submission No. EPA Registration No. 2724-759-270
Product Name: Adams D-Limonene Flea And Tick Shampoo For Dogs Cats Puppies
Liquid
Yes
Unknown
Site: Animal / Usage sur un animal domestique
Animal's Owner
Dog / Chien
Chihuahua
1
Female
0.25
Unknown
Skin
>8 hrs <= 24 hrs / >8 h <= 24 h
>8 hrs <=24 hrs / > 8 h < = 24 h
System
Persisted until death
No
No
Died
Treatment / Traitement
(eg. description of the frequency and severity of the symptoms
On August 9, 2012 the owner applied the product to the puppy. Later that evening, the owner noticed that the puppy was lethargic. The owner noticed that later that evening the dog had died while unattended. On August 10, 2012 the owner contacted the Animal Product Safety Service (APSS) to obtain help. The APSS veterinarian stated that severe signs would not be expected following the label use of the product. A necropsy was not available because the body had not been stored properly after death.
Death
The APSS veterinarian stated that the substance was considered to have a doubtful likelihood of causing the clinical situation.
Animal's Owner
Dog / Chien
Chihuahua
1
Male
0.25
Unknown
Skin
>24 hrs <=3 days / >24 h <=3 jours
>8 hrs <=24 hrs / > 8 h < = 24 h
System
Persisted until death
No
No
Died
Treatment / Traitement
(eg. description of the frequency and severity of the symptoms
On August 9, 2012 the owner noticed that the dog was moderately lethargic. On August 10, 2012 the owner observed that the dog's lethargy had become severe and he was unresponsive. Later that morning, the owner called her regular veterinarian, who was planning to come to the owner's house to assess the case. A short time later, the owner contacted the Animal Product Safety Service (APSS) to obtain help. The APSS veterinarian stated that sever signs are not expected. The APSS veterinarian also stated that more severe signs would not be expected following the label use of the shampoo product. During the consultation with the APSS, the owner noted that the dog's mucous membranes were pale. The APSS veterinarian recommended that the owner put Karo syrup or another sugary substance on the dog's mucous membranes; the owner said that she had frosting at home.
Death
On August 11, 2012 the owner called the APSS to update the case. The owner stated that on August 10, 2012 after consulting with the APSS, she put a sugary substance on the dog's mucous membranes. The owner also stated that the dog died on August 11, 2012. The APSS veterinarian recommended that the owner have her veterinarian call for information regarding a necropsy and to keep the dog's body chilled in the refrigerator so that a necropsy could be performed. On August 13, 2012 the owner's veterinary clinic called the APSS to discuss a necropsy. After several contacts with the clinic, on August 15, 2012 the body was picked up for the necropsy. On August 16, 2012 interim necropsy results were received. The interim results revealed a minimal nematode infection in the dog's small intestine. The histopathology results are pending and fresh tissue samples were saved in case ancillary testing was required. On August 21, 2012 final necropsy results were received. The results revealed no significant gross or histologic findings, and the head and brain were not available for examination. Based on the lack of significant findings, it is likely that an infectious etiology was not the cause of death; at this point, metabolic abnormalities such as hypoglycemia and potential D-Limonene toxicity remain possible differentials for the dog's death.