Incident Report

Subform I: General Information

1. Report Type.

New incident report

Incident Report Number: 2011-5824

2. Registrant Information.

Registrant Reference Number: 110098908

Registrant Name (Full Legal Name no abbreviations): Dow AgroSciences Canada Inc.

Address: Suite 2100, 450 - 1st Street S.W.

City: Calgary

Prov / State: Alberta

Country: Canada

Postal Code: T2P 5H1

3. Select the appropriate subform(s) for the incident.

Domestic Animal

4. Date registrant was first informed of the incident.

01-AUG-11

5. Location of incident.

Country: UNITED STATES

Prov / State: SOUTH CAROLINA

6. Date incident was first observed.

31-JUL-11

Product Description

7. a) Provide the active ingredient and, if available, the registration number and product name (include all tank mixes). If the product is not registered provide a submission number.

Active(s)

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PMRA Registration No.       PMRA Submission No.       EPA Registration No. 62719-0

Product Name: Grazon Herbicide Solution

• Active Ingredient(s)
  • 2,4-D (PRESENT AS AMINE SALTS : DIMETHYLAMINE SALT, DIETHANOLAMINE SALT, OR OTHER AMINE SALTS)
    • Guarantee/concentration 39.6 %
  • PICLORAM (PRESENT AS AMINE SALTS)
    • Guarantee/concentration 10.2 %

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7. b) Type of formulation.

Liquid

Application Information

8. Product was applied?

Yes

9. Application Rate.

Unknown

10. Site pesticide was applied to (select all that apply).

Site: Agricultural-Outdoor/Agricole-extérieur

Préciser le type: pasture

11. Provide any additional information regarding application (how it was applied, amount applied, the size of the area treated etc).

Owner sprayed his pasture last year with Grazon herbicide (3 pints to 1 acre). The owner did not wait the normal 30-40 days, but harvested it in 14 days. The forage was fed to the cattle from December to February. The owner is also a Turkey farmer and applied turkey litter to the pasture last year also. The exposure involved an unknown oral amount. The exposure was accidental, and occurred at the animal owner's home.

To be determined by Registrant

12. In your opinion, was the product used according to the label instructions?

Unknown

Subform III: Domestic Animal Incident Report

1. Source of Report

Medical Professional

2. Type of animal affected

Cow / Vache

3. Breed

Angus Cattle group of 135 (Bovine)

4. Number of animals affected

9

5. Sex

Female

6. Age (provide a range if necessary )

4

7. Weight (provide a range if necessary )

1350

lbs

8. Route(s) of exposure

Oral

Unknown

9. What was the length of exposure?

>1 mo <= 6 mos / > 1 mois < = 6 mois

10. Time between exposure and onset of symptoms

Unknown / Inconnu

11. List all symptoms

System

• General
  • Symptom - Death

• Reproductive System
  • Symptom - Stillbirth
  • Symptom - Birth defect
  • Specify - Deformed legs

12. How long did the symptoms last?

Unknown / Inconnu

13. Was medical treatment provided? Provide details in question 17.

No

14. a) Was the animal hospitalized?

No

14. b) How long was the animal hospitalized?

15. Outcome of the incident

Died

16. How was the animal exposed?

Accidental ingestion/Ingestion accident.

17. Provide any additional details about the incident

(eg. description of the frequency and severity of the symptoms

Nine calves were born in the past 3 weeks and all 9 were born dead. Had deformed legs. The veterinarian advised the owner that while it is possible to see birth defects, we would have expected to see severe toxicity signs in the cows first. Since that is not the case, it is unlikely that the Grazon is the cause of the birth defects. The turkey litter would depend on how it was composted and how broken down it was before it was applied. Recommend that owner have the calves necropsied.

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To be determined by Registrant

18. Severity classification (if there is more than 1 possible classification

Death

19. Provide supplemental information here

The medical professional indicated the following: Because the time course was poorly consistent, the amount was unknown consistent, and the findings were poorly consistent, this substance was considered to have doubtful likelihood of causing the clinical situation.