New incident report
Incident Report Number: 2011-2058
Registrant Reference Number: 2011CP008US
Registrant Name (Full Legal Name no abbreviations): Bayer Inc
Address: 77 Belfield Rd
City: Toronto
Prov / State: ON
Country: Canada
Postal Code: M9W 1G6
Domestic Animal
Country: UNITED STATES
Prov / State: UNKNOWN
PMRA Registration No. PMRA Submission No. EPA Registration No. 11556-118
Product Name: advantage 18
Liquid
Yes
Units: mL
Site: Animal / Usage sur un animal domestique
Medical Professional
Cat / Chat
domestic
1
Male
13
Unknown
Skin
>24 hrs <=3 days / >24 h <=3 jours
>8 hrs <=24 hrs / > 8 h < = 24 h
System
Persisted until death
No
No
Died
Treatment / Traitement
(eg. description of the frequency and severity of the symptoms
Twenty four hours after product application (1Dec10) the cat was deceased. The owner reports the cat had dyspnea shortly before death. DVM feels death was most likely due to a heart condition
Death
Sudden death no anticipated reaction with appropriate topical product administration, as not consistent with pharmaco-toxicological product profile. If any, typical adverse events such as behavioural disorders or skin reactions would be seen shortly after application. Systemic reactions not expected with spot-on application. In case of product ingestion, signs such as salivation, vomiting or lethargy would be seen. Most likely, cat`s death entirely unrelated with product use. Two other cats of same owner died 24 hours after product administration on different dates. Very uncommon as product used in past without adverse signs in all affected cats. For all cats, DVM suspected an underlying heart condition however other medical problems have to be considered as well in these geriatric cats. No necropsy performed to clarify cause of death.