Incident Report

Subform I: General Information

1. Report Type.

New incident report

Incident Report Number: 2008-2702

2. Registrant Information.

Registrant Reference Number: Prosar case 1-16296508

Registrant Name (Full Legal Name no abbreviations): Syngenta Crop Protection Canada, Inc.

Address: 140 Research Lane, Research Park

City: Guelph

Prov / State: Ontario

Country: Canada

Postal Code: N1G4Z3

3. Select the appropriate subform(s) for the incident.

Human

4. Date registrant was first informed of the incident.

06-JUN-08

5. Location of incident.

Country: UNITED STATES

Prov / State: CALIFORNIA

6. Date incident was first observed.

Unknown

Product Description

7. a) Provide the active ingredient and, if available, the registration number and product name (include all tank mixes). If the product is not registered provide a submission number.

Active(s)

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PMRA Registration No.       PMRA Submission No.       EPA Registration No.

Product Name: Daconil (non-specific)

• Active Ingredient(s)
  • CHLOROTHALONIL
    • Unknown

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PMRA Registration No.       PMRA Submission No.       EPA Registration No. 50534-209

Product Name: Daconil Weather Stik

• Active Ingredient(s)
  • CHLOROTHALONIL
    • Guarantee/concentration 54 %

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PMRA Registration No.       PMRA Submission No.       EPA Registration No. 50534-9

Product Name: Daconil 2787 Flowable Fungicide

• Active Ingredient(s)
  • CHLOROTHALONIL
    • Guarantee/concentration 40.4 %

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PMRA Registration No.       PMRA Submission No.       EPA Registration No.

Product Name: Diazinon

• Active Ingredient(s)
  • DIAZINON
    • Unknown

---

PMRA Registration No.       PMRA Submission No.       EPA Registration No.

Product Name: Paraquat (non-specific)

• Active Ingredient(s)
  • PARAQUAT
    • Unknown

---

PMRA Registration No.       PMRA Submission No.       EPA Registration No.

Product Name: Princep (non-specific)

• Active Ingredient(s)
  • SIMAZINE PLUS RELATED ACTIVE TRIAZINES
    • Unknown

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PMRA Registration No.       PMRA Submission No.       EPA Registration No. 100-794

Product Name: Subdue GR

• Active Ingredient(s)
  • METALAXYL-M (MEFENOXAM)
    • Guarantee/concentration 1 %

---

PMRA Registration No.       PMRA Submission No.       EPA Registration No. 100-796

Product Name: Subdue MAXX

• Active Ingredient(s)
  • METALAXYL-M (MEFENOXAM)
    • Guarantee/concentration 22 %

---

PMRA Registration No.       PMRA Submission No.       EPA Registration No.

Product Name: Subdue 2E

• Active Ingredient(s)
  • METALAXYL-M (MEFENOXAM)
    • Unknown

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PMRA Registration No.       PMRA Submission No.       EPA Registration No.

Product Name: Subdue (non-specific)

• Active Ingredient(s)
  • METALAXYL-M (MEFENOXAM)
    • Unknown

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7. b) Type of formulation.

Liquid

Granular

Other (specify)

Suspension

Application Information

8. Product was applied?

Yes

9. Application Rate.

Unknown

10. Site pesticide was applied to (select all that apply).

Site: Unknown / Inconnu

11. Provide any additional information regarding application (how it was applied, amount applied, the size of the area treated etc).

The patient worked as landscaper and gardener for multiple facilities and employers in (state) from about 1969-2007. During which time he and the co-workers in his direct proximity mixed and sprayed herbicides and other chemical products on weeds, plants, and grass as part of their employment. Following is a list of those chemical products thus far identified to which the patient was exposed during the course of his employment with multiple employers: 1) Registrant products: Daconil, Daconil Weather Stick, Daconil 2787 Flowable Fungicide, Diazinon, Paraquat, Princep, Subdue, Subdue 2E, Subdue GR, Subdue Maxx and 2) Multiple non-company products: 2, 4-D; 2-4-D Spray; 2,4-D Amine Spray; 2-4-D Ester; 2, 4-Dichlorophenol; Aliette; Aliette WDG Fungicide; Amitrol T; Bayleton; Bromomethane; Captan; Chlordane; Chlorothalonil; Cythion; Deildrin; Diazinon; Durspan Pro; Fore; Guthion; Joust; Karmex; Karmex DF; Karrnex IWC; Kamex XP; Kelthane; Lindane; Malathion; Mavrik Aquaflow; Methyl Bromide; Orth; Orthene; Orthenex; Ronstar; Ronstar WSP Herbicide; Ronstar 50 WSP Herbicide; Round Up; Simazine 4L; Simazine 90DF; Temek; Tempo; Terflan; Terflan AS; Trimec; Turflon; Turflon Ester; Vapam; and Vendex.

To be determined by Registrant

12. In your opinion, was the product used according to the label instructions?

Unknown

Subform II: Human Incident Report (A separate form for each person affected)

1. Source of Report.

Other

2. Demographic information of data subject

Sex: Male

Age: Unknown / Inconnu

3. List all symptoms, using the selections below.

System

• General
  • Symptom - Parkinson's Disease
  • Specify - Parkinson's disease

4. How long did the symptoms last?

Anticip. permanent/Permanence anticipée

5. Was medical treatment provided? Provide details in question 13.

Yes

6. a) Was the person hospitalized?

Yes

6. b) For how long?

Unknown

7. Exposure scenario

Occupational

8. How did exposure occur? (Select all that apply)

Application

9. If the exposure occured during application or re-entry, what protective clothing was worn? (select all that apply)

Unknown

10. Route(s) of exposure.

Unknown

11. What was the length of exposure?

>1 yr / > 1 an

12. Time between exposure and onset of symptoms.

Unknown / Inconnu

13. Provide any additional details about the incident (eg. description of the frequency and severity of the symptoms, type of medical treatment, results from medical tests, outcome of the incident, amount of pesticide exposed to, etc.)

1-16296508: The registrant was notified on 6/6/08 of litigation involving a male patient who had worked as landscaper and gardener for multiple facilities and employers in (state) from about 1969-2007. Summary from litigation: During this time he and co-workers in his direct proximity mixed and sprayed herbicides and other chemical products on weeds, plants, and grass as part of their employment. The chemical products to which the patient was exposed contained significant concentrations of pesticides which contain toxins, dioxin and organic solvents, benzene, as well as other organic solvents. As a direct and proximate result of said exposure to said toxic chemical products the patient sustained serious injuries to his internal organs, including Parkinson's Disease (first diagnosed in or about June of 2006). As medical treatment for Parkinson's Disease the patient has been hospitalized and undergone other medically necessary and lifesaving treatment and will continue to require such medical treatment in the future. Following is a list of those chemical products thus far identified to which the patient was exposed during the course of his employment with multiple employers, which contain certain toxins, and all of which caused his toxic injuries and occupational diseases: 1) Registrant products: Daconil, Daconil Weather Stick, Daconil 2787 Flowable Fungicide, Diazinon, Paraquat, Princep, Subdue, Subdue 2E, Subdue GR, Subdue Maxx and 2) Multiple non-company products: 2, 4-D; 2-4-D Spray; 2,4-D Amine Spray; 2-4-D Ester; 2, 4-Dichlorophenol; Aliette; Aliette WDG Fungicide; Amitrol T; Bayleton; Bromomethane; Captan; Chlordane; Chlorothalonil; Cythion; Deildrin; Diazinon; Durspan Pro; Fore; Guthion; Joust; Karmex; Karmex DF; Karrnex IWC; Kamex XP; Kelthane; Lindane; Malathion; Mavrik Aquaflow; Methyl Bromide; Orth; Orthene; Orthenex; Ronstar; Ronstar WSP Herbicide; Ronstar 50 WSP Herbicide; Round Up; Simazine 4L; Simazine 90DF; Temek; Tempo; Terflan; Terflan AS; Trimec; Turflon; Turflon Ester; Vapam; and Vendex. No additional information is available.

To be determined by Registrant

14. Severity classification.

Major

15. Provide supplemental information here.