Nouvelle déclaration d'incident
No de la demande: 2018-3590
Numéro de référence du titulaire d'homologation: USA-BAYERBAH-2018-US0042571 (Report 509157)
Nom du titulaire (nom légal complet, aucune abbréviation): Bayer inc
Adresse: 2920 Matheson BLVD
Ville: Mississaugua
État: ON
Pays: Canada
Code postal /Zip: L5W5R6
Incident chez un animal domestique
Pays: UNITED STATES
État: FLORIDA
ARLA No d'homologation ARLA No de la demande d'homologation EPA No d'homologation. 11556-155
Nom du produit: Seresto Collar unknown
Autre (préciser)
COLLAROui
Autres unités: Collar
Site: Animal / Usage sur un animal domestique
Inconnu
Propriétaire de l'animal
Dog / Chien
German Shepherd Dog
1
Homme
6
49.442
kg
Cutanée
Unknown / Inconnu
Unknown / Inconnu
Système
Persisted until death
Oui
Oui
3
Day(s) / Jour(s)
Mort
Treatment / Traitement
(p.ex. description des symptômes tels que la fréquence et la gravité
On 05Jul2018, the dog was examined by the veterinarian for unspecified illness. Radiographs and bloodwork were performed with unknown results. The dog was administered an unknown amount of unspecified fluids subcutaneously. The dog was started on unspecified doses of prednisone 20mg and doxycycline 100mg orally. On 06Jul2018, the dog collapsed in the rear limbs. On 07Jul2018, the dog was examined and hospitalized by the veterinarian as the dog was recumbent. The dog tested positive for Ehrlichiosis. Additional blood work was performed with unknown results. The dog had an intravenous catheter placed and was administered unspecified fluid therapy. The dog was also administered a doxycycline 100mg/ml injection. On 08Jul2018, the dog was continued on fluids, administered a dexamethasone 4mg/ml injection, then an unspecified wound he had was clipped and cleaned. On 09Jul2018, the fluids were continued and the dog was administered a metoclopramide 5mg/ml injection. The dog was tested for leptospirosis and hematocrit with unknown results. The dog died. No necropsy was performed. No further information is expected. This case is closed.
Mort
N - Unlikely Reported collapsed in the rear limbs, recumbency and unspecific wound are not typically seen with appropriate topical product administration. Signs likely associated with diagnosed Ehrlichiosis. Further, In this case, no ticks seen on dog. In case of attachment of ticks these will be killed and fall off the host within 24 to 48 hours after infestation without having had a blood meal, as a rule. However, attachment of single ticks and even sucking of blood and thus transfer of tick borne disease like Ehrlichiosis cannot be excluded while the collar is worn and simply reflects the labeled claim of efficacy that is not 100% against ticks especially when infestation pressure is high. Thus, infection with tick borne diseases despite wearing a collar can occur exceptionally and is consistent with the product's claimed efficacy. This issue is addressed in the product information. Death is not expected following appropriate topical product application as inconsistent with product's pharmacological profile. Oral exposure to the collar is not expected to cause serious signs either. An overdose of 5 collars around the neck was investigated in adult cats and dogs for an 8 months period and in 10 week old kittens and 7 week old puppies for a 6 months period without causing serious signs. Though time to onset is unknown for initial signs but long for other reported signs. Overall product relation is unlikely.