Nouvelle déclaration d'incident
No de la demande: 2014-6036
Numéro de référence du titulaire d'homologation: 140146279
Nom du titulaire (nom légal complet, aucune abbréviation): Wellmark International
Adresse: 100 Stone Road West, Suite 111
Ville: Guelph
État: Ontario
Pays: Canada
Code postal /Zip: N1G5L3
Incident chez un animal domestique
Pays: CANADA
État: BRITISH COLUMBIA
ARLA No d'homologation 28743 ARLA No de la demande d'homologation EPA No d'homologation.
Nom du produit: Zodiac Spot On II Flea Control For Cats And Kittens
Oui
Unités: mL
Site: Animal / Usage sur un animal domestique
Non
Professionnel de la santé
Cat / Chat
Domestic Shorthair
1
Femme
14.0
8.0
lbs
Cutanée
Unknown / Inconnu
>24 hrs <=3 days / >24 h <=3 jours
Système
Persisted until death
Oui
Oui
Inconnu
Mort
Treatment / Traitement
(p.ex. description des symptômes tels que la fréquence et la gravité
On November 9, 2014 the cat presented to the veterinary clinic with anemia, with a hematocrit of 25 percent, and a severe flea infestation, after the veterinarian removed at least 200 fleas with a flea comb, and then kept the cat overnight so the owner could treat the home for fleas. On November 10, 2014 the veterinary clinic administered a flea tablet to the cat and used the flea comb again (removed another 200 fleas). That afternoon the cat then had a seizure, bloody vomitus, and died as she was being taken out of the cage. On November 17, 2014 the attending veterinarian called the Animal Product Safety Service (APSS) to complain about how small the writing on the box was, which is why the elderly owner inappropriately dosed the cat. The attending veterinarian stated the cat was cremated. The APSS veterinarian stated the Zodiac spot on contains s-methoprene which is an insect growth regulator (IGR). The APSS veterinarian also stated if ingested there could be hypersalivation and nausea. The APSS veterinarian stated the flea tablet contains spinosad which is an anti-parasitic agent in the chemical class of tetracyclic macrolides. The APSS veterinarian further stated it is used in dogs at doses of 30-60 mg/kg for fleas and Plumb does not list a therapeutic dose for cats, but it is marketed for cats. The APSS veterinarian finally stated usually adverse reactions that can occur are vomiting, diarrhea, and mild lethargy; serious risks, seizures, and death are not expected. A necropsy was not available.
Mort
The APSS veterinarian stated that the Zodiac topical was not considered to be related to causing the clinical situation.