New incident report
Incident Report Number: 2017-4598
Registrant Reference Number: 170110637
Registrant Name (Full Legal Name no abbreviations): Wellmark International
Address: 100 Stone Road West, Suite 111
City: Guelph
Prov / State: Ontario
Country: Canada
Postal Code: N1G5L3
Domestic Animal
Country: UNITED STATES
Prov / State: INDIANA
PMRA Registration No. PMRA Submission No. EPA Registration No. 2724-813-89459
Product Name: Bio Spot Active Care Flea And Tick Spot On For Cats 5 Lbs and Over
Liquid
Yes
Units: mL
Site: Animal / Usage sur un animal domestique
Unknown
Animal's Owner
Cat / Chat
Domestic Unspecified
1
Male
28.0
17.5
lbs
Skin
<=15 min / <=15 min
<=30 min / <=30 min
System
Persisted until death
No
No
Died
Treatment / Traitement
(eg. description of the frequency and severity of the symptoms
Shortly after the product was applied on June 30, 2017 the cat developed symptoms. The owner then bathed the cat with liquid dish washing detergent and water. The owner noticed that the cat had developed an application site hemorrhage during the bath. The owner then contacted the Animal Product Safety Service (APSS) and the APSS technician stated that etofenprox is in the pyrethroid family and is safe to use on cats. The APSS technician also stated that it does not result in tremors or seizure activity that can be seen from other pyrethroids, since it is structurally different. The APSS technician also stated that dermal exposures may cause mild dermal irritation and hyperesthesia within the first 24-48 hours, possibly secondary alopecia from pruritus, and that oral exposures often result in hypersalivation, nausea, and possibly hiding because of the taste. The APSS technician continued by stating that some animals will hypersalivate just from the odor of the product. The APSS technician also stated that (s)- methoprene is an insect growth regulator (IGR) that disrupts the reproductive cycles of fleas, has low mammalian toxicity, may cause mild dermal irritation or sensitivity, usually from the carriers in the product, and that if ingested, there could be hypersalivation and nausea. The APSS assistant recommended the owner take the animal to a veterinarian, have the veterinarian call for information, and to call back with questions.
Death
On July 17, 2017 the owner called the APSS to update the case. The owner stated that the cat was not taken to a veterinarian, never recovered, and passed away that morning. A necropsy was declined as the cat had already been buried. It is unknown if the owner consulted a veterinarian about using the product on this geriatric cat.