New incident report
Incident Report Number: 2017-0586
Registrant Reference Number: 2017KP088
Registrant Name (Full Legal Name no abbreviations): Bayer Inc
Address: 2920 matheson BLVD
City: Mississaugua
Prov / State: ON
Country: Canada
Postal Code: L4W 5R6
Domestic Animal
Country: UNITED STATES
Prov / State: UNKNOWN
PMRA Registration No. PMRA Submission No. EPA Registration No. 11556-155
Product Name: Seresto Collar - Large Dog
Other (specify)
collarYes
Other Units: collar
Site: Animal / Usage sur un animal domestique
Other
Dog / Chien
Crossbreed
1
Female
1
40
lbs
Skin
>1 wk <=1 mo / > 1 sem < = 1 mois
>24 hrs <=3 days / >24 h <=3 jours
System
Unknown / Inconnu
Yes
Yes
1
Day(s) / Jour(s)
Died
Treatment / Traitement
(eg. description of the frequency and severity of the symptoms
On approximately 13Nov2016, the canine ingested an unknown amount of 1 Seresto Large Dog (Flumethrin-Imidacloprid) collar that was worn by another dog. On 15Nov2016, the canine exhibited hyperactivity and rolling behavior. She was examined by a veterinarian and was blind, hypersalivating, had muscle tremors, shaking and was laterally recumbent. Unknown treatments were instituted and the canine was hospitalized for continued care. On 15Nov2016, while hospitalized, the canine died. It was unknown if a necropsy was performed. No further information expected. Case closed.
Death
Dog ingested another dog's collar. Reported behavioural signs are unspecific and may have numerous other causes. Hypersalivation is unspecific sign, however may be associated with the oral ingestion of the product. Muscle tremor is not expected with appropriate topical product use. Oral product exposure may cause transient gastrointestinal sign but neurological disorder is not typically seen. Shaking is not expected after product application, however, may be associated with muscle tremor. Blindness, lateral recumbency and death are not expected following appropriate topical product application as inconsistent with products pharmacological profile. Oral exposure to the collar is not expected to cause serious signs either. An overdose of 5 collars around the neck was investigated in adult cats and dogs for an 8 months period and in 10 week old kittens and 7 week old puppies for a 6 months period without causing serious signs. Time to onset is long. Considering the product profile a connection is considered unlikely, however, as no necropsy performed to reveal other cause, product involvement is considered unassessable.