New incident report
Incident Report Number: 2017-0224
Registrant Reference Number: 160028672
Registrant Name (Full Legal Name no abbreviations): Wellmark International
Address: 100 Stone Road West, Suite 111
City: Guelph
Prov / State: Ontario
Country: Canada
Postal Code: N1G5L3
Domestic Animal
Country: UNITED STATES
Prov / State: TEXAS
PMRA Registration No. PMRA Submission No. EPA Registration No. 2724-490
Product Name: Vet Kem Siphotrol Plus II Premise Spray
Other (specify)
aerosolYes
Unknown
Site: Res. - In Home / Rés. - à l'int. maison
Unknown
Medical Professional
Cat / Chat
Domestic Shorthair
1
Female
9.0
7.0
lbs
Unknown
Unknown / Inconnu
>1 wk <=1 mo / > 1 sem < = 1 mois
System
Persisted until death
Yes
Unknown
Died
Contact treat.area/Contact surf. traitée
(eg. description of the frequency and severity of the symptoms
On February 29, 2016 the cat developed lethargy, anorexia, and dehydration. Later that day, the owner took the cat to the veterinarian, where a chemistry profile, complete blood count, and monitoring electrolytes were performed and the cat was given atropine. Later that day, the cat was diagnosed with anemia, with a hematocrit of 14.2 percent volume to volume (% v/v), renal disease, with serum creatinine of 2.4 mg/dL, elevated blood urea nitrogen, with blood urea nitrogen of 104.0 milligrams per deciliter (mg/dL), and hyperphosphatemia, with serum phosphorus of 0.0 mg/dL (high unmeasurable). The cat's dehydration worsened and the cat developed facial twitching, sternal recumbency, and hypothermia, with a temperature of 95.3 degrees Fahrenheit (deg F). Shortly after the attending veterinarian called the Animal Product Safety Service (APSS). The APSS veterinarian stated the active ingredients are pyrethroids, which often cause gagging, retching, lip licking, increased swallowing, and vomiting from the tingling/burning sensation in the mouth and throat. The APSS veterinarian also stated these signs often occur right after exposure, and are usually self-limiting. The APSS veterinarian further stated that central nervous system (CNS) signs are not expected. The APSS veterinarian recommended a diagnostic evaluation, fluid therapy (correct hydration), blood transfusion, treat renal failure, supportive and symptomatic care, and calling back with questions.
Death
The APSS veterinarian stated that the substance was considered to have a doubtful likelihood of causing the clinical situation. On March 1, 2016 the attending veterinarian called the APSS back. The attending veterinarian stated the cat was given fluid therapy at an unknown time. The attending veterinarian also stated that the cat was showing some improvement that morning and was given atropine. A few hours later the cat had a seizure, was given diazepam (1.25 mg), went into cardiac arrest and died. About an hour later the attending veterinarian called the APSS to further discuss the case. The attending veterinarian stated the cat's owner has other cats that have been treated for flea anemia and she has used this product in the past. The APSS veterinarian discussed the signs that could develop if there was access to the wet spray and anemia and acute kidney injury (AKI) are not expected from the product. The APSS veterinarian recommended a necropsy. The attending veterinarian stated she would discuss the necropsy with the owner.