New incident report
Incident Report Number: 2016-7526
Registrant Reference Number: 160145560
Registrant Name (Full Legal Name no abbreviations): Wellmark International
Address: 100 Stone Road West, Suite 111
City: Guelph
Prov / State: Ontario
Country: Canada
Postal Code: N1G5L3
Domestic Animal
Country: UNITED STATES
Prov / State: MISSOURI
PMRA Registration No. PMRA Submission No. EPA Registration No. 2724-803-270
Product Name: Adams Flea and Tick Spray for Dogs and Cats
Liquid
Yes
Unknown
Site: Animal / Usage sur un animal domestique
Unknown
Animal's Owner
Cat / Chat
Siamese
1
Male
5.0
12.0
lbs
Skin
>2 hrs <=8 hrs / >2 h <=8 h
Unknown / Inconnu
System
Persisted until death
No
No
Died
Treatment / Traitement
(eg. description of the frequency and severity of the symptoms
On September 28, 2016 the cat developed head shaking. That evening, the owner bathed the cat (liquid dish washing detergent (LDWD)). On September 29, 2016 the owner found the cat dead in the morning. The owner then contacted the Animal Product Safety Service (APSS). The APSS veterinarian stated we would not expect death as a direct result of the product use. The APSS veterinarian recommended a necropsy. The APSS veterinarian discussed with the owner taking the cat's body to the veterinary clinic for necropsy submission and having the veterinary clinic call for information regarding instructions. Later that morning, the attending veterinarian called the APSS to discuss necropsy submission instructions.
Death
The APSS veterinarian stated that the substance was considered to have a doubtful likelihood of causing the clinical situation. On October 4, 2016 the attending veterinarian called the APSS to state she had received a copy of the necropsy results. The gross necropsy report revealed the following morphologic diagnosis: heart (left ventricle) showed mild concentric hypertropy; lung showed diffuse, moderate edema; liver showed diffuse, moderate congestion; urinary bladder showed multifocal to coalescing, moderate, acute cystitis (presumptive); small intestine (jejunum) showed mild tapeworm parasitism; pancreas showed multifocal to coalescing, mild, acute pancreatitis; and right eye showed mild hyphema. Gross lesions observed in this animal were unspecific and a cause of death could not be determined. The histopath necropsy report revealed a morphologic diagnosis: the heart (left ventricle and interventricular septum) showed multifocal, moderate, myocardial disarray and fibrosis; the lung showed multifocal to coalescing, moderate, histiocytic interstitial pneumonia with type II pneumocyte hyperplasia and smooth muscle hypertrophy and hyperplasia. The histopathologic findings are highly suggestive of a chronic cardiac disease consistent with feline hypertrophic cardiomyopathy. Furthermore, pulmonary lesions were also characterized by a chronic process of unknown cause. It is uncertain, however, if the observed alterations elicited clinical abnormalities that contributed to the cause of death of this animal. Gross lesions observed in the urinary bladder and pancreas represented alterations of minimal significance on microscopic examination. Shortly after reviewing the report, the APSS veterinarian called the attending veterinarian back to discuss the necropsy and stated it was okay to give the owner a copy of the report. The APSS veterinarian also stated she would call the owner to discuss the necropsy results. The APSS veterinarian called the owner to go over the results and stated that it was highly suggestive of a chronic cardiac disease consistent with feline hypertrophic cardiomyopathy. The APSS veterinarian also stated the report revealed pulmonary lesions characterized by a chronic process of unknown cause. The APSS veterinarian discussed that underlying disease contributed to the death of the cat, spraying of the product may have been a trigger. The owner requested a copy of the necropsy report. The APSS veterinarian stated she was unable to mail a copy, but a copy could be obtained from the attending veterinary clinic. The APSS veterinarian called the attending veterinary clinic to let them know that the owner was interested in obtaining a copy of the necropsy results. The APSS veterinarian stated that hypertropic cardiomyopathy was considered to have a high likelihood of causing the clinical situation.