New incident report
Incident Report Number: 2014-6096
Registrant Reference Number: 2014CK383
Registrant Name (Full Legal Name no abbreviations): Bayer Inc
Address: 77 Belfield Rd
City: Toronto
Prov / State: ON
Country: Canada
Postal Code: M9W 1G6
Domestic Animal
Country: UNITED STATES
Prov / State: UNKNOWN
Unknown
PMRA Registration No. PMRA Submission No. EPA Registration No. Unknown
Product Name: Advantage II unknown
Liquid
Yes
Unknown
Site: Animal / Usage sur un animal domestique
Unknown
Animal's Owner
Cat / Chat
unknown
1
Unknown
16
Unknown
Skin
>1 wk <=1 mo / > 1 sem < = 1 mois
Unknown / Inconnu
System
Persisted until death
Unknown
Unknown
Died
Treatment / Traitement
(eg. description of the frequency and severity of the symptoms
On an unknown date post application, in 2013, the cat died. It is unknown if the cat was euthanized or if a necropsy was performed.Due to the sensitive nature of the communication, specific relevant event details were not obtained, nor will such be sought. The phone call communication was to discuss a current flea infestation and not to report the death of the cat.
Death
The information regarding the death of the cat was casually provided during an inquiry. The level of information is extremely low (product and animal details, medical history, chronology and necropsy not available) as the phone call communication was to discuss a current flea infestation and not to report the death of the cat. Nevertheless death is inconsistent with pharmaco-toxicological product profile and experience. No signs of allergic/anaphylactic reaction reported. Product has wide margin of safety. Oral LD50 in rat 642 mg/kg BW. 24-fold overdosage tolerated by cats without showing any side effect. Animal was at the height of life expectancy for the species and unknown if the animal was euthanized however need for euthenesia is not expected upon application of product. Time to onset is unknown. Considering all aspects, a product relation was considered unlikely.